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Interleukins are a subgroup of cytokines, molecules involved in the intercellular regulation of the immune system. The term interleukin was first coined in 1979 to refer to molecules that signal between different leucocyte types, although not exclusively restricted to leucocyte communication.
C J, Secombes, T, Wang, S, Bird
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Swollen Feet: Considering the Paradoxical Roles of Interleukins in Nephrotic Syndrome
Interleukins are a family of 40 bioactive peptides that act through cell surface receptors to induce a variety of intracellular responses. While interleukins are most commonly associated with destructive, pro-inflammatory signaling in cells, some also ...
Maria E. Kovalik +3 more
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Introduction: Community-acquired pneumonia (CAP) is still one of the major causes of morbidity and mortality worldwide. Pro-inflammatory and anti-inflammatory interleukins have been studied to elucidate the role that inflammation plays in its ...
Tripon Raluca Elena +6 more
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Background. The mediators of inflammation, which is the most important mechanism for the development of coronavirus infection, accompanied by various complications from the nervous system, both in the acute period of the disease and in the long term, are
P. E. Borodin
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Mast Cells and Interleukins [PDF]
Mast cells play a critical role in inflammatory diseases and tumor growth. The versatility of mast cells is reflected in their ability to secrete a wide range of biologically active cytokines, including interleukins, chemokines, lipid mediators ...
Ribatti, Domenico +5 more
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The roles and clinical applications of interleukins in endometrial carcinoma
As a common malignant tumor of the female reproductive system, endometrial carcinoma (EC) seriously endangers women’s health with an increasing incidence. The oncogenesis and progression of cancer are closely linked with immune microenvironment, of which
Yuqin Zang +14 more
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Targeting Certain Interleukins as Novel Treatment Options for Liver Fibrosis
The liver is a major metabolic organ and an immunologically complex organ. It produces and uses many substances such as acute phase proteins, cytokines, chemokines, and complementary components to maintain the balance between immunity and tolerance ...
Su Yeon An +4 more
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In this review we have summarized the large mass of information that has accumulated in recent years relative to the heterogeneous group of molecules known as the interleukins (IL), the lymphokines, and the cytokines that control the growth and differentiation of cells of the hematopoietic and lymphoid lineage and cells of other lineages. Our intent is
W, Strober, S P, James
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Interleukins and Ischemic Stroke
Ischemic stroke after cerebral artery occlusion is one of the major causes of chronic disability worldwide. Interleukins (ILs) play a bidirectional role in ischemic stroke through information transmission, activation and regulation of immune cells ...
Hua Zhu +10 more
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Interleukin 30 to Interleukin 40 [PDF]
Cytokines are important molecules that regulate the ontogeny and function of the immune system. They are small secreted proteins usually produced upon activation of cells of the immune system, including lymphocytes and myeloid cells. Many cytokines have been described, and several have been recognized as pivotal players in immune responses and in human
Catalan-Dibene, Jovani +2 more
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