Results 81 to 90 of about 387,713 (336)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

(De)Constructing the Disruption: Enacted Sensemaking and Sensegiving in Institutionally Plural Fields

open access: yesJournal of Organizational Sociology
If an event happens in the woods, and nobody responds to it, is it a disruption? In this paper, we address a gap in the organizational sociology literature about how events are constructed as “institutional disruptions” in institutionally plural fields ...
Kumar Amal, Higgins Monica C.
doaj   +1 more source

Customer flow, intermediaries, and the discovery of the equilibrium riskfree rate [PDF]

open access: yes, 2008
Macro announcements change the equilibrium riskfree rate. We find that treasury prices reflect part of the impact instantaneously, but intermediaries rely on their customer order flow in the 15 minutes after the announcement to discover the full impact ...
Menkveld, Albert J.   +2 more
core  

Understanding the supports needed for policy implementation: a comparative analysis of the placement of intermediaries across three mental health systems

open access: yesHealth Research Policy and Systems, 2019
BackgroundIntermediaries are organisations or programmes that work between policy-makers and service providers to facilitate effective implementation of evidence-informed policies, programmes and practices.
H. Bullock, J. Lavis
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Contractual Intermediaries [PDF]

open access: yes
This paper analyzes the role of third party intermediaries, such as courts and arbitrators, in contract enforcement. In our model, intermediaries compel contracted transfers and resolve disputes when requested to do so by the contracting agents. When the
Garey Ramey, Joel Watson
core  

The Licensing Function of Patent Intermediaries [PDF]

open access: yes, 2017
The contemporary patent marketplace is a complex ecosystem comprised of innovators and manufacturers who are often connected by a varied group of intermediaries.
Dubiansky, John E.
core   +1 more source

Fee-Setting Mechanisms: On Optimal Pricing by Intermediaries and Indirect Taxation [PDF]

open access: yes, 2012
Mechanisms according to which private intermediaries or governments charge transaction fees or indirect taxes are prevalent in practice. We consider a setup with multiple buyers and sellers and two-sided independent private information about ...
Loertscher, Simon, Niedermayer, Andras
core   +2 more sources

Banks as Tax Planning Intermediaries

open access: yesJournal of Accounting Research, 2018
We provide the first large‐scale empirical evidence of banks functioning as tax planning intermediaries. We posit that some banks specialize in assisting corporate clients with tax planning.
John Gallemore   +2 more
semanticscholar   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

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