Results 211 to 220 of about 46,488 (301)
Evaluating the potential of phenotypic age to enhance cardiovascular risk prediction over chronological age in the UK Biobank. [PDF]
Kwan KJS+10 more
europepmc +1 more source
Use of LC‐MS to characterize host cell protein removal during depth filtration
Abstract The removal of host cell proteins (HCPs) is crucial in biopharmaceutical production, as residual impurities can impact product safety and efficacy. While a number of studies have demonstrated that depth filtration can provide significant HCP removal, there is little information on its effectiveness in removing specific HCPs.
Liang‐Kai Chu+3 more
wiley +1 more source
Non-HDL-C and age-stratified mortality risk in the US general population: a population-based cohort study. [PDF]
Fu Z, Zhang W, Li S.
europepmc +1 more source
Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai+6 more
wiley +1 more source
Metabolic Dysfunction-Associated Steatotic Liver Disease: From a Very Low-Density Lipoprotein Perspective. [PDF]
Chen Y+6 more
europepmc +1 more source
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu+12 more
wiley +1 more source
Abstract Background Pancreatic cancer's aberrant lipid metabolism fuels cell growth, invasion, and metastasis, yet its impact on immune surveillance and immunotherapy is unclear. This study investigated how sterol regulatory element‐binding transcription factor 1 (SREBP1)‐driven lipid metabolism affects the tumor microenvironment (TME) in pancreatic ...
Mengyi Lao+12 more
wiley +1 more source
Lipoprotein(a) and Risk of Incident Atherosclerotic Cardiovascular Disease: Impact of High-Sensitivity C-Reactive Protein and Risk Variability Among Human Clinical Subgroups. [PDF]
Hoogeveen RC+7 more
europepmc +1 more source