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Cellular metabolism of human plasma intermediate-density lipoprotein (IDL)

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1990
The cellular metabolism of human plasma intermediate-density lipoprotein (IDL) was investigated in cultured human skin fibroblasts and hepG-2 cell in the absence and presence of exogenous recombinant or plasmatic apo E-3. IDL (d 1.006-1.019 g/ml) and LDL (d 1.019-1.063 g/ml) were prepared by centrifugation from the plasma of apo E-3/3 or 4/3 ...
G, Friedman   +3 more
openaire   +3 more sources

Increased transport of intermediate density lipoprotein (IDL) with cholesterol loading

Metabolism, 1983
Although cholesterol loading in man generally leads to an increase in plasma cholesterol and low density lipoprotein cholesterol in particular, the mechanism for this is unknown. Because IDL formation rises in cholesterol-fed rats we have measured the transport of IDL apoprotein B in 8 men during two dietary periods containing either 200 mg or 1700 mg ...
Paul J. Nestel, Timothy Billington
openaire   +2 more sources

Accumulation of intermediate density lipoprotein in the plasma of cholesterol-fed hypothyroid rats

Metabolism, 1983
Abstract The present study aimed to characterize the high cholesterol diet-induced hyperlipoproteinemia developed in thyroidectomized hypothyroid rats, in such animals the activities of hepatic triglyceride lipase having been shown to be decreased.
T, Murase, N, Yamada, H, Uchimura
openaire   +3 more sources

Ability of non-high-density lipoprotein cholesterol and calculated intermediate-density lipoprotein to identify nontraditional lipoprotein subclass risk factors in dialysis patients

American Journal of Kidney Diseases, 2004
Non-high-density lipoprotein cholesterol (non-HDL-C) and calculated intermediate-density lipoprotein cholesterol (IDL-C) have been proposed as surrogate markers to estimate apolipoprotein B-containing lipoproteins. The purpose of this study was to determine the validity of non-HDL-C and calculated IDL-C to predict nontraditional lipoprotein risk ...
Sharina S, Belani   +2 more
openaire   +3 more sources

Intermediate density lipoprotein cholesterol as the best lipoprotein predictor of atherosclerosis severity in the Watanabe Heritable Hyperlipidemic rabbit

Atherosclerosis, 1997
a Department of Clinical Biochemistry, Rigshospitalet, Uni6ersity of Copenhagen, Copenhagen, Denmark b Department of Clinical Biochemistry, Herle6 Hospital, Uni6ersity of Copenhagen, Herle6 Ring6ej 75, DK-2730 Herle6, Denmark c Department of Pathology, H6ido6re Hospital, Uni6ersity of Copenhagen, Copenhagen, Denmark d Department of Cardiology, H6ido6re
B G, Nordestgaard   +6 more
openaire   +3 more sources

Hyperlipemic-very low density lipoprotein, intermediate density lipoprotein and low density lipoprotein act synergistically with serotonin on vascular smooth muscle cell proliferation

Atherosclerosis, 2000
Previous studies have shown that very low density lipoprotein (VLDL), intermediate density lipoprotein (IDL) and low density lipoprotein (LDL) from hyperlipidemic plasma are more atherogenic than those from normal plasma. Since platelet aggregation at sites of atherosclerotic injury exposes the cells to high concentrations of serotonin (5HT), a known ...
S, Koba   +3 more
openaire   +3 more sources

An intermediate density lipoprotein of rat serum

Archives of Biochemistry and Biophysics, 1969
G R, Faloona, B N, Stewart, M, Fried
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The independent synthesis of intermediate density lipoproteins in type III hyperlipoproteinemia

Metabolism, 1982
The kinetics of VLDL (Sf 60-400) and IDL (Sf 12-60) B apoprotein were examined in five type III hyperlipoproteinemic subjects. The production rates for B apoprotein were significantly greater in the IDL fraction than in VLDL. Precursor-product relationships between VLDL and IDL B apoprotein illustrated that a significant proportion of IDL B apoprotein ...
M F, Reardon, M E, Poapst, G, Steiner
openaire   +2 more sources

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