Results 51 to 60 of about 46,488 (301)

Evidence for changing lipid management strategy to focus on non-high density lipoprotein cholesterol

Lipids in Health and Disease, 2019
Low-density lipoprotein cholesterol (LDL-C) has been recommended as the primary treatment target on lipid management in coronary heart disease (CHD) patients for past several decades.
Xin Su, Yi Kong, Daoquan Peng
doaj   +1 more source

Particle Size Distribution of Plasma Lipoproteins in Donkeys from Death Valley Compared to a Sampling of Horses

Animals, 2022
The clinical evaluation of lipid metabolism in equids is often limited to the measurement of total cholesterol and triglyceride concentrations. This provides a limited picture of metabolic state and general health, given the continuous exchange of lipid ...
Erin L. Goodrich, Erica Behling-Kelly
doaj   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Intermediate-density lipoprotein and cholesterol-rich very low density lipoprotein in angiographically determined coronary artery disease. [PDF]

Circulation, 1981
The relationship between the concentrations of intermediate-density lipoprotein (IDL) and other lipoproteins and the extent of coronary artery disease (CAD) was studied in 182 consecutive patients evaluated by selective coronary cineangiography. On univariate analysis, the extent of CAD correlated significantly and positively with very low density ...
Akira Nakayama, Susumu G. Miyamoto, Ryosei Ueda, Akira Genda, Hisanori Oiwake, Masayuki Ohta, Hiroshi Mabuchi, Ryoyu Takeda, Toshihiro Haba, Ryozo Tatami, Seigo Ito, Kosei G. Ueda, Tomio Kametani, Honin Kanaya, Junji Koizumi   +14 more
openaire   +3 more sources

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht, Majd Machour, Inbal Michael, Maria Bulatova, Janette Zavin, Shulamit Levenberg   +5 more
wiley   +1 more source

Impaired receptor-mediated catabolism of low density lipoproteins in fasted rabbits.

Journal of Lipid Research, 1984
Plasma cholesterol levels of New Zealand white rabbits, fasted for 9 days, increased 4-fold owing to elevated levels of low density lipoproteins and intermediate density lipoproteins.
J B Stoudemire, G Renaud, D M Shames, R J Havel   +3 more
doaj  

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

Endogenous sterol synthesis is not required for regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by low density lipoprotein

Journal of Lipid Research, 1987
It has been proposed that an endogenously synthesized oxysterol mediates the regulation of cholesterol biosynthesis by low density lipoprotein in cultured mammalian cells.
E Burki, J Logel, M Sinensky
doaj  

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source