Results 141 to 150 of about 948,768 (269)

Image_4_ADAM17-Mediated Reduction in CD14++CD16+ Monocytes ex vivo and Reduction in Intermediate Monocytes With Immune Paresis in Acute Pancreatitis and Acute Alcoholic Hepatitis.JPEG

, 2019
Impaired immune responses and increased susceptibility to infection characterize acute inflammatory conditions such as pancreatitis and alcoholic hepatitis and are major causes of morbidity and mortality.
Robert Hutchins (7311494), William Alazawi (4672714), Kathryn Waller (7311485), Anja de Jong (4351993), Charlotte James (493050), David Kelsell (110422), Laura Blackmore (7311488), Michael O'Dwyer (573461), Yun Ma (119475), Andrew Stagg (7311491)   +9 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Сhanges of the functional phenotype of circulating monocytes during pregnancy

Медицинская иммунология
Rearrangement of the immune system during pregnancy is a strictly controlled, dynamic process in which the first and third trimesters are, respectively, pro-inflammatory, and anti-inflammatory periods.
N. G. Bukhtueva, O. Yu. Leplina, E. Ya. Shevela, M. A. Tikhonova, N. M. Pasman, A. A. Ostanin, E. R. Chernykh   +6 more
doaj   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Image_6_ADAM17-Mediated Reduction in CD14++CD16+ Monocytes ex vivo and Reduction in Intermediate Monocytes With Immune Paresis in Acute Pancreatitis and Acute Alcoholic Hepatitis.JPEG

, 2019
Impaired immune responses and increased susceptibility to infection characterize acute inflammatory conditions such as pancreatitis and alcoholic hepatitis and are major causes of morbidity and mortality.
Robert Hutchins (7311494), William Alazawi (4672714), Kathryn Waller (7311485), Anja de Jong (4351993), Charlotte James (493050), David Kelsell (110422), Laura Blackmore (7311488), Michael O'Dwyer (573461), Yun Ma (119475), Andrew Stagg (7311491)   +9 more
core   +1 more source

Intermediate monocytes induced by IFN-γ inhibit cancer metastasis by promoting NK cell activation through FOXO1 and interleukin-27. [PDF]

J Immunother Cancer, 2022
Wang R, Bao W, Pal M, Liu Y, Yazdanbakhsh K, Zhong H.   +5 more
europepmc   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Image_5_ADAM17-Mediated Reduction in CD14++CD16+ Monocytes ex vivo and Reduction in Intermediate Monocytes With Immune Paresis in Acute Pancreatitis and Acute Alcoholic Hepatitis.JPEG

, 2019
Impaired immune responses and increased susceptibility to infection characterize acute inflammatory conditions such as pancreatitis and alcoholic hepatitis and are major causes of morbidity and mortality.
Robert Hutchins (7311494), William Alazawi (4672714), Kathryn Waller (7311485), Anja de Jong (4351993), Charlotte James (493050), David Kelsell (110422), Laura Blackmore (7311488), Michael O'Dwyer (573461), Yun Ma (119475), Andrew Stagg (7311491)   +9 more
core   +1 more source

Phenotypic and functional characteristics of monocyte subsets in the blood and bone marrow of Indian subjects with Visceral Leishmaniasis.

PLoS Neglected Tropical Diseases
Visceral leishmaniasis (VL) is a potentially fatal parasitic infection caused by Leishmania donovani in India. L. donovani is an obligate intracellular protozoan residing mostly in macrophages of the reticuloendothelial system throughout chronic ...
Gulafsha Kausar, Shashi Bhushan Chauhan, Ritirupa Roy, Vimal Verma, Sundaram Pandey, Aziza Niyaz, Jaya Chakravarty, Christian R Engwerda, Susanne Nylen, Rajiv Kumar, Mary E Wilson, Shyam Sundar   +11 more
doaj   +1 more source