Results 1 to 10 of about 1,881,470 (286)

Increased Frequency of Circulating Classical Monocytes in Patients with Rosacea [PDF]

Clinical, Cosmetic and Investigational Dermatology, 2021
Cuie Gao,1 Lan Ge,1 Dewei Chen,2 Mengjie Zhang,2 Li Zhao,2 Wenying Liu,1 Shuguang Chen,1 Juan Wang,1 Cunjian Zhou,1 Xingwang Zhao,1 Shifei Li,1 Zhiqiang Song,1 Jian Li1 1Department of Dermatology, Southwest Hospital, Army Medical University, Chongqing ...
Gao C, Ge L, Chen D, Zhang M, Zhao L, Liu W, Chen S, Wang J, Zhou C, Zhao X, Li S, Song Z, Li J   +12 more
doaj   +6 more sources

Non-classical monocytes contribute to innate immune training in cattle [PDF]

Innate Immunity, 2022
Innate immune training is defined as a property of innate immune cells to react stronger to a secondary contact with pathogens. Induction of innate immune training has been reported for a variety of pathogens and selected pattern recognition receptor ...
Lisa-Marie Schünemann, Hans-Joachim Schuberth   +1 more
doaj   +5 more sources

Non-classical monocytes are biased progenitors of wound healing macrophages during soft tissue injury [PDF]

Scientific Reports, 2017
Successful tissue repair requires the activities of myeloid cells such as monocytes and macrophages that guide the progression of inflammation and healing outcome.
Claire E. Olingy, Cheryl L. San Emeterio, Molly E. Ogle, Jack R. Krieger, Anthony C. Bruce, David D. Pfau, Brett T. Jordan, Shayn M. Peirce, Edward A. Botchwey   +8 more
doaj   +4 more sources

Transcriptomic signatures of classical monocytes reveal pro-inflammatory modules and heterogeneity in polyarticular juvenile idiopathic arthritis [PDF]

Frontiers in Immunology
Introduction Polyarticular juvenile idiopathic arthritis (pJIA) is a childhood-onset autoimmune disease. Immune cells contribute to persistent inflammation observed in pJIA.
Eduardo Borba, Rosa M R Pereira, Camille Figueiredo   +2 more
exaly   +6 more sources

NR4A1 deletion promotes pro-angiogenic polarization of macrophages derived from classical monocytes in a mouse model of neovascular age-related macular degeneration [PDF]

Journal of Neuroinflammation, 2023
Background Neovascular age-related macular degeneration causes vision loss from destructive angiogenesis, termed choroidal neovascularization (CNV). Cx3cr1 −/− mice display alterations in non-classical monocytes and microglia with increased CNV size ...
Steven Droho, Andrew P. Voigt, Jacob K. Sterling, Amrita Rajesh, Kyle S. Chan, Carla M. Cuda, Harris Perlman, Jeremy A. Lavine   +7 more
doaj   +3 more sources

Transcriptomic characterization of classical monocytes highlights the involvement of immuno-inflammation in bone erosion in Rheumatoid Arthritis [PDF]

Frontiers in Immunology, 2023
Introduction Evidence-based data suggest that under inflammatory conditions, classical monocytes are the main source of osteoclasts and might be involved in bone erosion pathophysiology.
Georg Schett, Rosa M R Pereira, Bidossessi Wilfried Hounkpe   +2 more
exaly   +3 more sources

Production of MHCII‐expressing classical monocytes increases during aging in mice and humans [PDF]

Aging Cell, 2022
Aging is associated with increased monocyte production and altered monocyte function. Classical monocytes are heterogenous and a shift in their subset composition may underlie some of their apparent functional changes during aging.
Berenice A Benayoun, Helen Goodridge
exaly   +3 more sources

Targeting immunosuppressive Ly6C+ classical monocytes reverses anti-PD-1/CTLA-4 immunotherapy resistance. [PDF]

Front Immunol, 2023
Introduction Despite significant clinical advancement with the use of immune checkpoint blockade (ICB) in non-small cell lung cancer (NSCLC) there are still a major subset of patients that develop adaptive/acquired resistance.
Rodriguez BL, Chen L, Li Y, Miao S, Peng DH, Fradette JJ, Diao L, Konen JM, Alvarez FRR, Solis LM, Yi X, Padhye A, Gibson LA, Ochieng JK, Zhou X, Wang J, Gibbons DL.   +16 more
europepmc   +5 more sources

GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammation [PDF]

Cell Reports, 2021
SUMMARY Lipopolysaccharide (LPS) can either promote or prevent T helper 2 (Th2) cell allergic responses. However, the underlying mechanism remains unknown.
Amber Papillion, Holly Bachus, Alexander F Rosenberg   +2 more
exaly   +3 more sources

Non-classical monocytes frequency and serum vitamin D₃ levels are linked to diabetic foot ulcer associated with peripheral artery disease. [PDF]

J Diabetes Investig, 2023
Peripheral artery disease (PAD) serves as a risk factor for diabetic foot ulcers (DFUs). PAD pathology involves atherosclerosis and impaired immunity. Non‐classical monocytes are believed to have an anti‐inflammatory role.
Hammad R, Abdel Wahab MA, Farouk N, Zakaria MY, Eldosoky MA, Elmadbouly AA, Tahoun SA, Mahmoud E, Khirala SK, Mohammed AR, Emam WA, Abo Elqasem AA, Kotb FM, Abd Elghany RAE.   +13 more
europepmc   +2 more sources