Results 21 to 30 of about 1,881,470 (286)

Predominantly Pro-Inflammatory Phenotype with Mixed M1/M2 Polarization of Peripheral Blood Classical Monocytes and Monocyte-Derived Macrophages among Patients with Excessive Ethanol Intake. [PDF]

Antioxidants (Basel), 2023
Excessive alcohol consumption impairs the immune system, induces oxidative stress, and triggers the activation of peripheral blood (PB) monocytes, thereby contributing to alcoholic liver disease (ALD).
Fernández-Regueras M, Carbonell C, Salete-Granado D, García JL, Gragera M, Pérez-Nieto MÁ, Morán-Plata FJ, Mayado A, Torres JL, Corchete LA, Usategui-Martín R, Bueno-Martínez E, Rojas-Pirela M, Sabio G, González-Sarmiento R, Orfao A, Laso FJ, Almeida J, Marcos M.   +18 more
europepmc   +2 more sources

Transcriptomic and proteomic profiling reveals distinct pathogenic features of peripheral non-classical monocytes in systemic lupus erythematosus

Clinical Immunology, 2023
Peripheral blood monocytes propagate inflammation in systemic lupus erythematosus (SLE). Three major populations of monocytes have been recognized namely classical (CM), intermediate (IM) and non-classical monocytes (NCM).
Theodora Manolakou, Martina Samiotaki, Aggelos Banos   +2 more
exaly   +2 more sources

High levels of PF4, VEGF-A, and classical monocytes correlate with the platelets count and inflammation during active tuberculosis. [PDF]

Front Immunol, 2022
Platelets play a major role in coagulation and hemostasis; evidence supports the hypothesis that they also contribute to immunological processes. Increased platelet counts have been associated with poor prognosis in tuberculosis (TB).
Urbán-Solano A, Flores-Gonzalez J, Cruz-Lagunas A, Pérez-Rubio G, Buendia-Roldan I, Ramón-Luing LA, Chavez-Galan L.   +6 more
europepmc   +2 more sources

Single-cell sequencing of PBMC characterizes the altered transcriptomic landscape of classical monocytes in BNT162b2-induced myocarditis. [PDF]

Front Immunol, 2022
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been the most dangerous threat to public health worldwide for the last few years, which led to the development of the novel mRNA vaccine (BNT162b2).
Hwang N, Huh Y, Bu S, Seo KJ, Kwon SH, Kim JW, Yoon BK, Ahn HS, Fang S.   +8 more
europepmc   +2 more sources

Circulating classical monocytes are associated with CD11c+ macrophages in human visceral adipose tissue [PDF]

Scientific Reports, 2017
Immune cell accumulation in adipose tissue (AT) is associated with the development of AT inflammation, resulting in metabolic dysfunction. Circulating immune cell patterns may reflect immune cell accumulation in expanding AT.
K. Wouters, K. Gaens, M. Bijnen, K. Verboven, J. Jocken, S. Wetzels, Erwin P M Wijnands, D. Hansen, M. V. van Greevenbroek, A. Duijvestijn, E. Biessen, E. Blaak, C. Stehouwer, C. Schalkwijk   +13 more
semanticscholar   +7 more sources

Alterations in Th17 Cells and Non-Classical Monocytes as a Signature of Subclinical Coronary Artery Atherosclerosis during ART-Treated HIV-1 Infection. [PDF]

Cells
Cardiovascular disease (CVD) remains an important comorbidity in people living with HIV-1 (PLWH) receiving antiretroviral therapy (ART). Our previous studies performed in the Canadian HIV/Aging Cohort Study (CHACS) (>40 years-old; Framingham Risk Score ...
Wiche Salinas TR, Zhang Y, Gosselin A, Rosario NF, El-Far M, Filali-Mouhim A, Routy JP, Chartrand-Lefebvre C, Landay AL, Durand M, Tremblay CL, Ancuta P, Canadian HIV and Aging Cohort Study (CHACS).   +12 more
europepmc   +2 more sources

Neutrophil-Derived Cathelicidin Promotes Adhesion of Classical Monocytes [PDF]

Circulation Research, 2013
Rationale: The leukocyte response in acute inflammation is characterized by an initial recruitment of neutrophils preceding a second wave of monocytes. Neutrophil-derived granule proteins were suggested to hold an important role in this cellular switch.
Wantha, Sarawuth, Alard, Jean-Eric, Megens, Remco T. A., van der Does, Anne M., Doering, Yvonne, Drechsler, Maik, Pham, Christine T. N., Wang, Ming-Wei, Wang, Ji-Min, Gallo, Richard L., von Hundelshausen, Philipp, Lindbom, Lennart, Hackeng, Tilman, Weber, Christian, Soehnlein, Oliver   +14 more
openaire   +5 more sources

CEACAM 1, 3, 5 and 6 -positive classical monocytes correlate with interstitial lung disease in early systemic sclerosis. [PDF]

Front Immunol, 2022
Background Systemic sclerosis (SSc) is a multiple-organ disease characterized by vascular damage, autoimmunity, and tissue fibrosis. Organ injuries such as interstitial lung diseases (ILD), resulting from inflammatory and fibrosis processes, lead to poor
Yokoyama K, Mitoma H, Kawano S, Yamauchi Y, Wang Q, Ayano M, Kimoto Y, Ono N, Arinobu Y, Akashi K, Horiuchi T, Niiro H.   +11 more
europepmc   +2 more sources

Reduced frequencies and functional impairment of dendritic cell subsets and non-classical monocytes in myelodysplastic syndromes. [PDF]

Haematologica, 2022
In myelodysplastic syndromes (MDS) the immune system is involved in pathogenesis as well as in disease progression. Dendritic cells (DC) are key players of the immune system by serving as regulators of immune responses.
Van Leeuwen-Kerkhoff N, Westers TM, Poddighe PJ, Povoleri GAM, Timms JA, Kordasti S, De Gruijl TD, Van de Loosdrecht AA.   +7 more
europepmc   +2 more sources

Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes [PDF]

EMBO Molecular Medicine, 2013
We used a novel approach of cytostatically induced leucocyte depletion and subsequent reconstitution with leucocytes deprived of classical (inflammatory/Gr1hi) or non‐classical (resident/Gr1lo) monocytes to dissect their differential role in ...
Oliver Soehnlein, Maik Drechsler, Yvonne Döring, Dirk Lievens, Helene Hartwig, Klaus Kemmerich, Almudena Ortega‐Gómez, Manuela Mandl, Santosh Vijayan, Delia Projahn, Christoph D. Garlichs, Rory R. Koenen, Mihail Hristov, Esther Lutgens, Alma Zernecke, Christian Weber   +15 more
doaj   +5 more sources