PLoS ONE, 2012 We have conducted the first study to determine the diagnostic potential of the CD14++CD16+ intermediate monocytes as compared to the pro-angiogenic subset of CD14++CD16+TIE2+ TIE2-expressing monocytes (TEMs) in cancer.
Dominic Schauer +10 more
doaj +7 more sources
Intermediate monocytes correlate with CXCR3+ Th17 cells but not with bone characteristics in untreated early rheumatoid arthritis. [PDF]
PLoS ONE, 2021 BackgroundRheumatoid arthritis (RA) is associated with development of generalized osteoporosis. Bone-degrading osteoclasts are derived from circulating precursor cells of monocytic lineage, and the intermediate monocyte population is important as ...
Christina Drevinge +10 more
doaj +5 more sources
Phenotypic characterization of human intermediate monocytes [PDF]
Frontiers in Immunology, 2013 A full understanding of the immune system requires full characterization of the cells, and its subsets, which play a role in the process of host defense. The expression pattern of cell surface molecules serves as a major criterion for assigning cells into discrete subsets.
Daniëlle eHijdra +8 more
doaj +6 more sources
Intermediate Monocytes with PD-L1 and CD62L Expression as a Possible Player in Active SARS-CoV-2 Infection [PDF]
Viruses, 2022 Monocytes play a role in viral biology, but little is known about the monocyte subpopulation in the course of COVID-19 disease. The aim of the study was the analysis of classical, intermediate and non-classical monocytes with expression of PD-L1 and ...
Elżbieta Rutkowska +4 more
doaj +4 more sources
Association of intermediate monocytes with dengue severity among the pediatric population of Odisha, India [PDF]
Scientific ReportsDengue virus (DENV) infection in children exhibits varied clinical presentations, wherein the role of monocytes is important in the innate immune response. In this study, laboratory-confirmed DENV pediatric patients (n = 120), with DENV-2 infection, were
Manoj Kumar Dash +9 more
doaj +5 more sources
Intermediate monocytes contribute to pathologic immune response in Leishmania braziliensis infections. [PDF]
Journal of Infectious Diseases, 2015 Ulcer development in patients with cutaneous leishmaniasis (CL) caused by Leishmania braziliensis is associated with high levels of tumor necrosis factor (TNF). We found that early after infection, before ulcer development, the frequency of CD16(+) (both intermediate [CD14(+)CD16(+)] and nonclassical [CD14(dim)CD16(+)]) monocytes was increased in the ...
Lucas P Carvalho +2 more
exaly +5 more sources
Recruitment of IL‐1β‐producing intermediate monocytes enhanced by C5a contributes to the development of malignant pleural effusion [PDF]
Thoracic Cancer, 2022 Background Monocytes are involved in tumor growth and metastasis, but the distribution of monocyte phenotypes and their role in the development of malignant pleural effusion (MPE) remains unknown.
Lisha Luo +9 more
doaj +2 more sources
Higher circulating intermediate monocytes are associated with cognitive function in women with HIV. [PDF]
JCI Insight, 2021 BACKGROUND Identifying a quantitative biomarker of neuropsychiatric dysfunction in people with HIV (PWH) remains a significant challenge in the neuroHIV field. The strongest evidence to date implicates the role of monocytes in central nervous system (CNS) dysfunction in HIV, yet no study has examined monocyte ...
Veenhuis RT +11 more
europepmc +5 more sources
Higher proportion of non-classical and intermediate monocytes in newly diagnosed multiple myeloma patients in Egypt: A possible prognostic marker [PDF]
African Journal of Laboratory Medicine, 2021 Background: Interaction between multiple myeloma (MM) cells and proximal monocytes is expected during plasma cell proliferation. However, the role of monocyte subsets in the disease progression is unknown.
Asmaa M. Zahran +5 more
doaj +2 more sources
Fasting plasma methylglyoxal concentrations are associated with higher numbers of circulating intermediate and non-classical monocytes but with lower activation of intermediate monocytes: the Maastricht Study. [PDF]
J Endocrinol InvestAbstract Purpose Elevated methylglyoxal (MGO) levels and altered immune cell responses are observed in diabetes. MGO is thought to modulate immune cell activation. The current study investigated whether fasting or post-glucose-load plasma MGO concentrations are associated with circulating immune cell counts and ...
Zhang X +7 more
europepmc +4 more sources