Results 1 to 10 of about 68,467 (167)

Intermediate monocytes but not TIE2-expressing monocytes are a sensitive diagnostic indicator for colorectal cancer. [PDF]

PLoS ONE, 2012
We have conducted the first study to determine the diagnostic potential of the CD14++CD16+ intermediate monocytes as compared to the pro-angiogenic subset of CD14++CD16+TIE2+ TIE2-expressing monocytes (TEMs) in cancer.
Dominic Schauer, Patrick Starlinger, Christian Reiter, Nikolaus Jahn, Philipp Zajc, Elisabeth Buchberger, Thomas Bachleitner-Hofmann, Michael Bergmann, Anton Stift, Thomas Gruenberger, Christine Brostjan   +10 more
doaj   +7 more sources

Intermediate monocytes correlate with CXCR3+ Th17 cells but not with bone characteristics in untreated early rheumatoid arthritis. [PDF]

PLoS ONE, 2021
BackgroundRheumatoid arthritis (RA) is associated with development of generalized osteoporosis. Bone-degrading osteoclasts are derived from circulating precursor cells of monocytic lineage, and the intermediate monocyte population is important as ...
Christina Drevinge, Julia M Scheffler, Catalin Koro-Arvidsson, Daniel Sundh, Hans Carlsten, Inger Gjertsson, Catharina Lindholm, Mattias Lorentzon, Anna Rudin, Anna-Karin Hultgård Ekwall, Ulrika Islander   +10 more
doaj   +6 more sources

Intermediate Monocytes with PD-L1 and CD62L Expression as a Possible Player in Active SARS-CoV-2 Infection [PDF]

Viruses, 2022
Monocytes play a role in viral biology, but little is known about the monocyte subpopulation in the course of COVID-19 disease. The aim of the study was the analysis of classical, intermediate and non-classical monocytes with expression of PD-L1 and ...
Elżbieta Rutkowska, Iwona Kwiecień, Krzysztof Kłos, Piotr Rzepecki, Andrzej Chciałowski   +4 more
doaj   +6 more sources

Intermediate Monocytes Contribute to Pathologic Immune Response inLeishmania braziliensisInfections [PDF]

Journal of Infectious Diseases, 2015
Ulcer development in patients with cutaneous leishmaniasis (CL) caused by Leishmania braziliensis is associated with high levels of tumor necrosis factor (TNF). We found that early after infection, before ulcer development, the frequency of CD16(+) (both intermediate [CD14(+)CD16(+)] and nonclassical [CD14(dim)CD16(+)]) monocytes was increased in the ...
Lucas P Carvalho, Tais M Campos, Phillip Scott   +2 more
exaly   +7 more sources

Phenotypic characterization of human intermediate monocytes [PDF]

Frontiers in Immunology, 2013
A full understanding of the immune system requires full characterization of the cells, and its subsets, which play a role in the process of host defense. The expression pattern of cell surface molecules serves as a major criterion for assigning cells into discrete subsets.
Daniëlle eHijdra, Daniëlle eHijdra, Adriane DM Vorselaars, Jan C Grutters, Jan C Grutters, Anke ME Claessen, Ger T Rijkers, Ger T Rijkers, Ger T Rijkers   +8 more
doaj   +6 more sources

Association of intermediate monocytes with dengue severity among the pediatric population of Odisha, India [PDF]

Scientific Reports
Dengue virus (DENV) infection in children exhibits varied clinical presentations, wherein the role of monocytes is important in the innate immune response. In this study, laboratory-confirmed DENV pediatric patients (n = 120), with DENV-2 infection, were
Manoj Kumar Dash, Sagnika Samal, Shailesh Rout, Rajesh Kumar Bhola, Janeka Gartia, Ishani Saha, Chinmay Kumar Behera, Hamida Hamdi, Mahesh Chandra Sahu, Biswadeep Das   +9 more
doaj   +5 more sources

Intermediate Monocytes and Cytokine Production Associated With Severe Forms of Chagas Disease [PDF]

Frontiers in Immunology, 2019
يتم تصنيف الخلايا الأحادية وفقًا لتعبير CD14 و CD16 إلى كلاسيكية (تعويضية) ومتوسطة (التهابية) وغير كلاسيكية. قيمت هذه الدراسة تواتر الخلايا الأحادية والعلاقة بين النسب المئوية للمجموعات الفرعية من الخلايا الأحادية ومستويات سيتوكينات الدم لدى مرضى شاغاس الكولومبيين بأشكال سريرية مختلفة.
Gonzalez Jm, Natalia I Bolaños, Concepción Judith Puerta Bula   +2 more
exaly   +7 more sources

Recruitment of IL‐1β‐producing intermediate monocytes enhanced by C5a contributes to the development of malignant pleural effusion [PDF]

Thoracic Cancer, 2022
Background Monocytes are involved in tumor growth and metastasis, but the distribution of monocyte phenotypes and their role in the development of malignant pleural effusion (MPE) remains unknown.
Lisha Luo, Shuanglinzi Deng, Wei Tang, Xinyue Hu, Feifei Yin, Huan Ge, Jiale Tang, Zhonghua Liao, Xiaozhao Li, Juntao Feng   +9 more
doaj   +2 more sources

Decoding the diabetes-pancreatic adenocarcinoma connection: the critical role of PILRA in intermediate monocyte activity [PDF]

BMC Medical Genomics
Diabetes is a well-known risk factor for pancreatic adenocarcinoma (PAAD), yet the underlying molecular mechanisms remain unclear. This study employs single-cell sequencing to analyze gene expression patterns and uses Mendelian randomization to assess ...
Chao Lv, Zhenhua Liu, Shuaimin Zhang, Shengpeng Yang, Guoliang Wang, Jingjing Xiao   +5 more
doaj   +5 more sources

Higher circulating intermediate monocytes are associated with cognitive function in women with HIV. [PDF]

JCI Insight, 2021
BACKGROUND Identifying a quantitative biomarker of neuropsychiatric dysfunction in people with HIV (PWH) remains a significant challenge in the neuroHIV field. The strongest evidence to date implicates the role of monocytes in central nervous system (CNS) dysfunction in HIV, yet no study has examined monocyte ...
Veenhuis RT, Williams DW, Shirk EN, Abreu CM, Ferreira EA, Coughlin JM, Brown TT, Maki PM, Anastos K, Berman JW, Clements JE, Rubin LH.   +11 more
europepmc   +5 more sources