Monocyte adaptations in patients with obesity during a 1.5 year lifestyle intervention
BackgroundObesity is associated with chronic, low-grade inflammation, which is reflected in altered peripheral blood monocyte characteristics. The aim of this study was to analyze the monocyte subset composition (classical (CM), intermediate (IM) and non-
Eline S. van der Valk +9 more
doaj +1 more source
Monocyte Phenotypes and Physical Activity in Patients with Carotid Atherosclerosis
Atherosclerosis is associated with low-grade inflammation involving circulating monocytes. It has been shown that the levels of intermediate pro-inflammatory monocytes are associated with cardiovascular mortality and risk of ischemic stroke.
Mathilde Mura +10 more
doaj +1 more source
Chronic non-infectious inflammation of low intensity is the most important mechanism of development and progression in atherosclerosis. Under the conditions of persistent non-resolving inflammation observed in the vascular wall and atherosclerotic plaque
V. V. Genkel +8 more
doaj +1 more source
Lymphokines Enhance the Capacity of Human Monocytes to Secrete Reactive Oxygen Intermediates [PDF]
Supernatants from mitogen- or antigen-stimulated human blood mononuclear cells enhanced the capacity of human monocytes or monocyte-derived macrophages (MDM) to release H(2)O(2) or O(2) in response to phorbol myristate acetate or zymosan. The stimulatory effect of lymphokines (LK) lasted approximately 5 d, regardless of the time of their addition ...
A, Nakagawara +3 more
openaire +2 more sources
Pregnancy and preeclampsia affect monocyte subsets in humans and rats. [PDF]
INTRODUCTION: Both nonclassical and intermediate monocytes have been implicated in different inflammatory conditions. We hypothesized that these monocytes would increase during pregnancy, a condition associated with generalized activation of inflammatory
Barbro N Melgert +11 more
doaj +1 more source
Non-classical and intermediate monocytes in patients following venous thromboembolism: Links with inflammation [PDF]
Monocyte subsets are involved in atherosclerotic vascular disease and its thromboembolic complications. Moreover, the role of monocytes has been suggested in the pathogenesis of venous thromboembolism (VTE).We hypothesized that pro-inflammatory non-classical and intermediate monocytes are increased in the first months following VTE.We enrolled 70 ...
Wypasek, Ewa +5 more
openaire +3 more sources
Additional analyses of monocytes reveals diversity of surface expression on classical, intermediate, and non-classical monocytes. [PDF]
A. Examples of monocyte gating from a healthy volunteer control and DLBCL patient. Mononuclear cells were gated from CD45+ WBCs ([WBCs]). CD14+ monocytes were gated from [MNCs].
Allan B. Dietz (709538) +7 more
core +1 more source
Quantitative whole-cell MALDI-TOF MS fingerprints distinguishes human monocyte sub-populations activated by distinct microbial ligands [PDF]
Conventionally, human monocyte sub-populations are classified according to surface marker expression into classical (CD14(++)CD16(-)), intermediate (CD14(++)CD16(+)) and non-classical (CD14(+)CD16(++)) lineages. The involvement of non-classical monocytes,
Brunisholz, René +11 more
core +1 more source
Intermediate Monocytes and Circulating Endothelial Cells: Interplay with Severity of Atherosclerosis in Patients with Coronary Artery Disease and Type 2 Diabetes Mellitus [PDF]
The aim was to investigate the association of monocyte heterogeneity and presence of circulating endothelial cells with the severity of coronary atherosclerosis in patients with coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM).
Kologrivova I +7 more
europepmc +2 more sources
Can intermediate monocytes predict response to infliximab therapy in sarcoidosis? [PDF]
Responders to infliximab therapy have more intermediate monocytes at baseline compared with non-responders http://ow.ly ...
Daniëlle, Hijdra +7 more
openaire +2 more sources

