Results 21 to 30 of about 948,768 (269)

Decoding the resistin-CAP1 pathway in intermediate monocytes mediating liver allograft rejection

Journal of Hepatology
Lymphocytes are widely recognized as the primary mediators of cellular rejection after liver transplantation. However, conventional immunosuppressive regimens that target lymphocytes, such as calcineurin phosphatase inhibitors, corticosteroids, or lymphocyte-depleting antibodies, can only partially mitigate rejection while inducing severe adverse ...
Peijun Yang, Kaishan Tao, Juzheng Yuan
exaly   +3 more sources

Circulating intermediate monocytes produce TARC in sarcoidosis

Allergology International, 2020
Izumi Kishimoto, Chuyen Thi Hong Nguyen, Naotomo Kambe, Nhung Thi My Ly, Yoko Ueki, Ikuko Ueda-Hayakawa, Hiroyuki Okamoto   +6 more
doaj   +3 more sources

Phenotypic and functional heterogeneity of human intermediate monocytes based on HLA‐DR expression

Immunology & Cell Biology, 2018
AbstractHuman blood monocytes are subclassified as classical, intermediate and nonclassical. In this study, it was shown that conventionally defined human intermediate monocytes can be divided into two distinct subpopulations with mid‐ and high‐level surface expression of HLA‐DR (referred to as DRmid and DRhi intermediate monocytes).
Eanna P Connaughton, Serika Naicker, Shirley A Hanley, Stephanie M Slevin, John K Eykelenboom, Noel F Lowndes, Timothy O'Brien, Rhodri Ceredig, Matthew D Griffin, Michael C Dennedy   +9 more
openaire   +3 more sources

Intermediate monocytes in blood correlate with subclinical vascular changes in lupus nephritis. [PDF]

Lupus Sci Med
Garg S, McCoy SS, Hartel I, Muhlstock A, Raval AN, Bartels C.   +5 more
europepmc   +4 more sources

Decoding the diabetes-pancreatic adenocarcinoma connection: the critical role of PILRA in intermediate monocyte activity

BMC Medical Genomics
Diabetes is a well-known risk factor for pancreatic adenocarcinoma (PAAD), yet the underlying molecular mechanisms remain unclear. This study employs single-cell sequencing to analyze gene expression patterns and uses Mendelian randomization to assess ...
Chao Lv, Zhenhua Liu, Shuaimin Zhang, Shengpeng Yang, Guoliang Wang, Jingjing Xiao   +5 more
doaj   +4 more sources

Contribution of monocyte subpopulations to the pathogenesis and therapy outcome of type 1 diabetes management in pediatric patients [PDF]

Frontiers in Immunology
Type 1 diabetes mellitus (T1D) is an autoimmune disease characterized by the destruction of pancreas β cells causing impairment in insulin secretion. Despite various factors contributing to T1D, i.e., immunological, genetic, and environmental factors ...
Aleksandra Starosz, Milena Jamiołkowska-Sztabkowska, Sandra Murawska, Barbara Głowińska-Olszewska, Artur Bossowski, Kamil Grubczak   +5 more
doaj   +2 more sources

Classical monocytes from patients with pancreatic ductal adenocarcinoma exhibit a significantly altered transcriptome profile compared with healthy volunteers [PDF]

, 2014
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorPancreatic Ductal Adenocarcinoma (PDAC) affects approximately 8000 people every ...
Cook, Jenny Anne
core   +4 more sources

Intermediate monocytes expansion and homing markers expression in COVID-19 patients associate with kidney dysfunction. [PDF]

Clin Exp Med, 2023
Patients with severe SARS-CoV-2 infection have an overwhelming inflammatory response characterized by remarkable organs monocyte infiltration. We performed an immunophenotypic analysis on circulating monocytes in 19 COVID-19 patients in comparison with ...
Dentone C, Fenoglio D, Parodi A, Altosole T, Di Biagio A, Bozzano F, Nasi G, Vena A, Fabbi M, Ferrera F, Bruzzone B, Giacomini M, Giacobbe DR, Pelosi P, De Maria A, Bassetti M, De Palma R, Filaci G.   +17 more
europepmc   +2 more sources

Interferon as a macrophage activating factor. I. Enhancement of cytotoxicity by fresh and matured human monocytes in the absence of other soluble signals [PDF]

, 1983
The cytolytic activity ofhuman peripheral blood monocytes in vitro against K-562 human leukaemic target cells was stimulated by human fibroblast (fi-) and leucocyte (a-) interferon (IFN). Stimulation was by up to several times the corresponding control
Virelizier, JL, Dean, RT
core   +6 more sources

Expression of M2-associated molecules in circulating monocyte subsets in fertile non-pregnant women and pregnant women with uncomplicated pregnancy

Медицинская иммунология, 2022
In humans circulating monocytes include classical (CD14++CD16- ), intermediate (CD14++CD16+) and non-classical/alternative (CD14+CD16++) monocytes, which in turn can be activated via the classical or alternative pathway.
E. Ya. Shevela, N. G. Bukhtueva, M. A. Tikhonova, O. Yu. Leplina, N. M. Pasman, E. R. Chernykh   +5 more
doaj   +1 more source