Results 1 to 10 of about 71,540 (227)

Immune complex-induced haptokinesis in human non-classical monocytes [PDF]

Frontiers in Immunology, 2023
Formation and deposition of immune complexes (ICs) are hallmarks of various autoimmune diseases. Detection of ICs by IC receptors on leukocytes induces downstream signaling and shapes the local immune response. In many cases the pathological relevance of
Sophie L. Preuß, Stephanie Oehrl, Hao Zhang, Thomas Döbel, Ulrike Engel, Jennifer L. Young, Jennifer L. Young, Jennifer L. Young, Joachim P. Spatz, Joachim P. Spatz, Knut Schäkel   +10 more
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Revising CX3CR1 Expression on Murine Classical and Non-classical Monocytes [PDF]

Frontiers in Immunology, 2020
In mice, monocytes (Mo) are conventionally described as CX3CR1low classical Mo (CMo) and CX3CR1high non-classical Mo (NCMo) based on the expression of EGFP in Cx3cr1+/EGFP mice and by analogy with human CX3CR1 expression.
Aïda Meghraoui-Kheddar, Aïda Meghraoui-Kheddar, Sandrine Barthelemy, Alexandre Boissonnas, Christophe Combadière   +4 more
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Non-classical monocytes contribute to innate immune training in cattle [PDF]

Innate Immunity, 2022
Innate immune training is defined as a property of innate immune cells to react stronger to a secondary contact with pathogens. Induction of innate immune training has been reported for a variety of pathogens and selected pattern recognition receptor ...
Lisa-Marie Schünemann, Hans-Joachim Schuberth   +1 more
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The slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood

Frontiers in Immunology, 2023
IntroductionPeripheral monocytes in humans are conventionally divided into classical (CL, CD14++CD16−), intermediate (INT, CD14++CD16+) and non-classical (NC, CD14dim/−CD16++) cells, based on their expression levels of CD14 and CD16.
Nicola Tamassia, Francisco Bianchetto-Aguilera, Sara Gasperini, Alessio Grimaldi, Alessio Grimaldi, Claudia Montaldo, Federica Calzetti, Elisa Gardiman, Ilaria Signoretto, Monica Castellucci, Vincenzo Barnaba, Marco Tripodi, Marco Antonio Cassatella   +12 more
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Nr4a1-dependent non-classical monocytes are important for macrophage-mediated wound healing in the large intestine [PDF]

Frontiers in Immunology, 2023
IntroductionMacrophages play an important role in intestinal wound healing. However, the trajectories from circulating monocytes to gut macrophages are incompletely understood.MethodsTaking advantage of mice depleted for non-classical monocytes due to ...
Karin Heidbreder, Katrin Sommer, Maximilian Wiendl, Tanja M. Müller, Tanja M. Müller, Imke Atreya, Imke Atreya, Kai Hildner, Kai Hildner, Markus F. Neurath, Markus F. Neurath, Sebastian Zundler, Sebastian Zundler   +12 more
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Non-classical monocytes are biased progenitors of wound healing macrophages during soft tissue injury [PDF]

Scientific Reports, 2017
Successful tissue repair requires the activities of myeloid cells such as monocytes and macrophages that guide the progression of inflammation and healing outcome.
Claire E. Olingy, Cheryl L. San Emeterio, Molly E. Ogle, Jack R. Krieger, Anthony C. Bruce, David D. Pfau, Brett T. Jordan, Shayn M. Peirce, Edward A. Botchwey   +8 more
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Helminth species specific expansion and increased TNF-alpha production of non-classical monocytes during active tuberculosis. [PDF]

PLoS Neglected Tropical Diseases, 2021
Both Mycobacterium tuberculosis infection and helminths may affect innate immune mechanisms such as differential effects on monocytes towards the non-classical and intermediate subsets that favor bacterial persistence.
Gezahegn Bewket, Amare Kiflie, Ebba Abate, Olle Stendahl, Thomas Schön, Robert Blomgran   +5 more
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Non‐classical monocytes frequency and serum vitamin D3 levels are linked to diabetic foot ulcer associated with peripheral artery disease [PDF]

Journal of Diabetes Investigation, 2023
Aims/Introduction Peripheral artery disease (PAD) serves as a risk factor for diabetic foot ulcers (DFUs). PAD pathology involves atherosclerosis and impaired immunity. Non‐classical monocytes are believed to have an anti‐inflammatory role.
Reham Hammad, Maisa A Abdel Wahab, Nehal Farouk, Mohamed Yahia Zakaria, Mona A Eldosoky, Asmaa A Elmadbouly, Sara A Tahoun, Eman Mahmoud, Seham K Khirala, Amena Rezk Mohammed, Wafaa Abdelaziz Emam, Asmaa A Abo Elqasem, Fatma M Kotb, Rasha Abd Elaziz Abd Elghany   +13 more
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Expression of VEGFA-mRNA in classical and MSX2-mRNA in non-classical monocytes in patients with spondyloarthritis is associated with peripheral arthritis [PDF]

Scientific Reports, 2021
Spondyloarthritis (SpA) is characterized by chronic inflammation and structural damage involving spine and peripheral joints. Monocytes, as part of innate immune system, following migration into affected tissue, may play a role in the pathogenesis of SpA.
Małgorzata Stec, Michał Seweryn, Mariusz Korkosz, Zofia Guła, Rafał Szatanek, Kazimierz Węglarczyk, Magdalena Rutkowska-Zapała, Marzena Lenart, Marcin Czepiel, Jarosław Czyż, Jarosław Baran, Anna Gruca, Kamila Wojnar-Lasoń, Paweł Wołkow, Maciej Siedlar   +14 more
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Blood monocytes and their subsets: established features and open questions

Frontiers in Immunology, 2015
In contrast to the past reliance on morphology the identification and enumeration of blood monocytes is nowadays done with monoclonal antibodies and flow cytometry and this allows for subdivision into classical, intermediate and non-classical monocytes ...
Loems eZiegler-Heitbrock
doaj   +3 more sources