Results 11 to 20 of about 11,145,052 (236)

Increased frequency of IL-6-producing non-classical monocytes in neuromyelitis optica spectrum disorder [PDF]

Journal of Neuroinflammation, 2017
Background Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disease of the central nervous system that preferentially affects the optic nerves, spinal cord, and area postrema. A series of evidence suggested that B cells play a
Byung Soo Kong, Yeseul Kim, Ga Young Kim, Jae-Won Hyun, Su-Hyun Kim, Aeran Jeong, Ho Jin Kim   +6 more
doaj   +3 more sources

The slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood [PDF]

Frontiers in Immunology, 2023
IntroductionPeripheral monocytes in humans are conventionally divided into classical (CL, CD14++CD16−), intermediate (INT, CD14++CD16+) and non-classical (NC, CD14dim/−CD16++) cells, based on their expression levels of CD14 and CD16.
Nicola Tamassia, Francisco Bianchetto-Aguilera, Sara Gasperini, Alessio Grimaldi, Alessio Grimaldi, Claudia Montaldo, Federica Calzetti, Elisa Gardiman, Ilaria Signoretto, Monica Castellucci, Vincenzo Barnaba, Marco Tripodi, Marco Antonio Cassatella   +12 more
doaj   +2 more sources

Early monocyte subset signatures predict outcomes in unvaccinated COVID-19 patients [PDF]

Frontiers in Immunology
IntroductionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized by complex immune responses, with monocytes playing a central role in disease pathogenesis.ObjectiveThis study aimed to evaluate the profiles of monocytes
Fabrício Marcus Silva Oliveira, Mônica Maria Magalhães Caetano, Larissa Lilian de Oliveira, Juliana Vaz de Melo Mambrini, Marina Santos Rezende, Marina Pinheiro Rocha Fantini, Marina Pinheiro Rocha Fantini, Tiago Antônio De Oliveira Mendes, Henrique Cerqueira Guimarães, Henrique Cerqueira Guimarães, Jacqueline Araújo Fiuza, Jacqueline Araújo Fiuza, Soraya Torres Gaze   +12 more
doaj   +2 more sources

Diminished Non-Classical Monocytes in the Blood Associate with Disease Severity in Alcoholic Hepatitis. [PDF]

Clin Exp Gastroenterol, 2021
Elisabeth Busk Rasmussen,1 Lotte Lindgreen Eriksen,2 Stinne Ravn Greisen,1 Anne Louise Hansen,1 Mikkel Carstensen,1 Thomas Damgaard Sandahl,2 Sidsel Støy,2 Tue Wenzel Kragstrup1,3 1Department of Biomedicine, Aarhus University, Aarhus, Denmark ...
Rasmussen EB, Eriksen LL, Greisen SR, Hansen AL, Carstensen M, Sandahl TD, Støy S, Kragstrup TW.   +7 more
europepmc   +2 more sources

Hepatic Ly6C^Lo Non-Classical Monocytes Have Increased Nr4a1 (Nur77) in Murine Biliary Atresia. [PDF]

J Clin Med, 2022
Biliary atresia (BA) is a rapidly progressive perinatal inflammatory disease, resulting in liver failure. Hepatic Ly6CLo non-classical monocytes promote the resolution of perinatal liver inflammation during rhesus rotavirus-mediated (RRV) BA in mice.
Mohamedaly S, Levy CS, Korsholm C, Alkhani A, Rosenberg K, Ashouri JF, Nijagal A.   +6 more
europepmc   +2 more sources

Ly6c^Lo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation. [PDF]

Sci Rep, 2020
Perinatal hepatic inflammation can have devastating consequences. Monocytes play an important role in the initiation and resolution of inflammation, and their diverse functions can be attributed to specific cellular subsets: pro-inflammatory or classical
Alkhani A, Levy CS, Tsui M, Rosenberg KA, Polovina K, Mattis AN, Mack M, Van Dyken S, Wang BM, Maher JJ, Nijagal A.   +10 more
europepmc   +2 more sources

Comprehensive cell surface proteomics defines markers of classical, intermediate and non-classical monocytes. [PDF]

Sci Rep, 2020
Monocytes are a critical component of the cellular innate immune system, and can be subdivided into classical, intermediate and non-classical subsets on the basis of surface CD14 and CD16 expression.
Ravenhill BJ, Soday L, Houghton J, Antrobus R, Weekes MP.   +4 more
europepmc   +8 more sources

Non-classical monocytes as mediators of tissue destruction in arthritis. [PDF]

Ann Rheum Dis, 2018
OBJECTIVES: Bone destruction in rheumatoid arthritis is mediated by osteoclasts (OC), which are derived from precursor cells of the myeloid lineage.
Puchner A, Saferding V, Bonelli M, Mikami Y, Hofmann M, Brunner JS, Caldera M, Goncalves-Alves E, Binder NB, Fischer A, Simader E, Steiner CW, Leiss H, Hayer S, Niederreiter B, Karonitsch T, Koenders MI, Podesser BK, O'Shea JJ, Menche J, Smolen JS, Redlich K, Blüml S.   +22 more
europepmc   +3 more sources

Classical monocytes from patients with pancreatic ductal adenocarcinoma exhibit a significantly altered transcriptome profile compared with healthy volunteers [PDF]

, 2014
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorPancreatic Ductal Adenocarcinoma (PDAC) affects approximately 8000 people every ...
Cook, Jenny Anne
core   +4 more sources

Monocyte adaptations in patients with obesity during a 1.5 year lifestyle intervention

Frontiers in Immunology, 2022
BackgroundObesity is associated with chronic, low-grade inflammation, which is reflected in altered peripheral blood monocyte characteristics. The aim of this study was to analyze the monocyte subset composition (classical (CM), intermediate (IM) and non-
Eline S. van der Valk, Eline S. van der Valk, Daniël S. Mulder, Daniël S. Mulder, Tessa Kouwenhoven, Tessa Kouwenhoven, Nicole M. A. Nagtzaam, Elisabeth F. C. van Rossum, Willem A. Dik, Pieter J. M. Leenen   +9 more
doaj   +1 more source