The Ontogeny of Monocyte Subsets [PDF]
Frontiers in Immunology, 2019 Classical and non-classical monocytes, and the macrophages and monocyte-derived dendritic cells they produce, play key roles in host defense against pathogens, immune regulation, tissue repair and many other processes throughout the body.
Alberto Yanez +2 more
exaly +6 more sources
Abnormal Changes of Monocyte Subsets in Patients With Sjögren’s Syndrome [PDF]
Frontiers in Immunology, 2022 BackgroundRecent studies have proven the existence of distinct monocyte subsets, which play a significant role in the development of some rheumatic diseases such as systemic lupus erythematosus (SLE).
, Guixiu Shi, Rongjuan Chen
exaly +4 more sources
Monocyte subsets and monocyte-related chemokines in Takayasu arteritis [PDF]
Scientific Reports, 2023 The pathogenesis of Takayasu arteritis (TAK) is poorly understood and no previous studies have analyzed monocytes in TAK. This study evaluated monocyte subsets and monocyte-related chemokines in the peripheral blood of TAK patients and healthy controls ...
Mariana Freitas de Aguiar +8 more
doaj +5 more sources
Distinct Roles of Monocyte Subsets in Cancer [PDF]
CellsWhile the distinct roles of lymphocyte populations are well characterized in adaptive immunity, the phenotypic and functional diversity of innate immune cells is less explored.
Maria Amparo Sahagun Cortez +3 more
doaj +5 more sources
Monocyte Subsets: Phenotypes and Function in Tuberculosis Infection [PDF]
Frontiers in Immunology, 2018 Monocytes are critical defense components that play an important role in the primary innate immune response. The heterogeneous nature of monocytes and their ability to differentiate into either monocyte-derived macrophages or monocyte-derived dendritic ...
Ramalingam Bethunaickan +2 more
exaly +6 more sources
Transcriptional characteristics and functional validation of three monocyte subsets during aging [PDF]
Immunity & Ageing, 2023 Background Age-associated changes in immunity are inextricably linked to chronic inflammation and age-related diseases, the impact of aging on monocyte subsets is poorly understood. Methods Flow cytometry was applied to distinguish three monocyte subsets
Chen Wang +7 more
doaj +2 more sources
The CCR2+ Monocyte Subsets Increase in Obese Boys but Not Girls with Abnormally High Carotid Intima-Media Thickness: A Pilot Study [PDF]
Journal of Cardiovascular Development and Disease, 2022 The differential contribution of monocyte subsets expressing the C-C chemokine receptor 2 (CCR2) to subclinical atherosclerosis in girls and boys is unclear.
María José Garcés-Hernández +11 more
doaj +2 more sources
Phenotypic and functional alterations of monocyte subsets with aging. [PDF]
Immun Ageing, 2022 Abstract Background It has been widely accepted that monocytes are one of the central mediators contributing to inflammaging. However, it remains unclear whether aged monocytes, similar to aged T cells, have characteristics of hyperactivation and increased expression of co-inhibitory molecules.
Cao Y +12 more
europepmc +4 more sources
Phenotypic and functional characteristics of monocyte subsets in the blood and bone marrow of Indian subjects with Visceral Leishmaniasis. [PDF]
PLoS Neglected Tropical DiseasesVisceral leishmaniasis (VL) is a potentially fatal parasitic infection caused by Leishmania donovani in India. L. donovani is an obligate intracellular protozoan residing mostly in macrophages of the reticuloendothelial system throughout chronic ...
Gulafsha Kausar +11 more
doaj +2 more sources
Towards a refined definition of monocyte subsets [PDF]
Frontiers in Immunology, 2013 In a nomenclature proposal published in 2010 monocytes were subdivided into classical and nonclassical cells and in addition an intermediate monocyte subset was proposed.
Loems eZiegler-Heitbrock +1 more
doaj +3 more sources