Distinct Roles of Monocyte Subsets in Cancer [PDF]
CellsWhile the distinct roles of lymphocyte populations are well characterized in adaptive immunity, the phenotypic and functional diversity of innate immune cells is less explored.
Maria Amparo Sahagun Cortez +3 more
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Monocyte subsets and monocyte-related chemokines in Takayasu arteritis [PDF]
Scientific Reports, 2023 The pathogenesis of Takayasu arteritis (TAK) is poorly understood and no previous studies have analyzed monocytes in TAK. This study evaluated monocyte subsets and monocyte-related chemokines in the peripheral blood of TAK patients and healthy controls ...
Mariana Freitas de Aguiar +8 more
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Phenotypic and functional characteristics of monocyte subsets in the blood and bone marrow of Indian subjects with Visceral Leishmaniasis. [PDF]
PLoS Neglected Tropical DiseasesVisceral leishmaniasis (VL) is a potentially fatal parasitic infection caused by Leishmania donovani in India. L. donovani is an obligate intracellular protozoan residing mostly in macrophages of the reticuloendothelial system throughout chronic ...
Gulafsha Kausar +11 more
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Abnormal Changes of Monocyte Subsets in Patients With Sjögren’s Syndrome [PDF]
Frontiers in Immunology, 2022 BackgroundRecent studies have proven the existence of distinct monocyte subsets, which play a significant role in the development of some rheumatic diseases such as systemic lupus erythematosus (SLE).
Yan He +13 more
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Transcriptional characteristics and functional validation of three monocyte subsets during aging [PDF]
Immunity & Ageing, 2023 Background Age-associated changes in immunity are inextricably linked to chronic inflammation and age-related diseases, the impact of aging on monocyte subsets is poorly understood. Methods Flow cytometry was applied to distinguish three monocyte subsets
Chen Wang +7 more
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Susceptibility and response of human blood monocyte subsets to primary dengue virus infection. [PDF]
PLoS ONE, 2012 Human blood monocytes play a central role in dengue infections and form the majority of virus infected cells in the blood. Human blood monocytes are heterogeneous and divided into CD16(-) and CD16(+) subsets.
Kok Loon Wong +5 more
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Effect of spironolactone on monocyte subsets in atrial fibrillation: IMPRESS-AF randomised controlled trial [PDF]
Scientific ReportsBackground Monocyte subsets differentially influence pathophysiology of heart failure and atrial fibrillation (AF) through inflammation, fibrosis, and angiogenesis. Spironolactone has antifibrotic properties.
Farhan Shahid +3 more
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Contrasting behavior between the three human monocyte subsets in dengue pathophysiology [PDF]
iScience, 2022 Summary: Monocytes are known to play a critical role in dengue pathophysiology. However, which monocyte subset expresses what inflammatory mediator(s) and what transcriptional features distinguish each of the monocyte subset in vivo remain poorly ...
Deepti Maheshwari +20 more
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Long‐lasting changes in circulating dendritic cell and monocyte subsets, and altered expression of EMR2, CD97 and EMR3 on these cells in the posttraumatic course [PDF]
Clinical & Translational ImmunologyObjectives Traumatic injury triggers the rapid release of damage‐associated patterns (DAMPs). Dendritic cells (DCs) and monocytes play key roles in sensing, processing, and presenting DAMPs to naïve T cells.
Leyu Zheng +4 more
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MONOCYTE SUBSETS IN RELAPSING REMITTING MULTIPLE SCLEROSIS EGYPTIAN PATIENTS [PDF]
Ain Shams Medical Journal, 2023 Background: Although many types of immune cells are involved in multiple sclerosis (MS) progression, activated monocytes are believed to be one of the first to arrive at the brain and initiate inflammation.
Hala Mohamed +4 more
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