Results 31 to 40 of about 85,833 (243)

Foxp3+Helios+ regulatory T cells are associated with monocyte subsets and their PD-1 expression during acute HIV-1 infection

BMC Immunology, 2019
Background Helios has been reported to stabilize regulatory T (Treg) suppressive function. Programmed cell death protein 1 (PD-1) expression in three human monocyte subsets modulates immune responses.
Lifeng Liu, Qiuyue Zhang, Peng Chen, Na Guo, Aixin Song, Xiaojie Huang, Wei Xia, Li Li, Christiane Moog, Hao Wu, Bin Su, Tong Zhang   +11 more
doaj   +1 more source

Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2009
Monocytes and macrophages play active roles in atherosclerosis, a chronic inflammatory disease that is a leading cause of death in the developed world. The prevailing paradigm states that, during human atherogenesis, monocytes accumulate in the arterial intima and differentiate into macrophages, which then ingest oxidized lipoproteins ...
Swirski, Filip K, Weissleder, Ralph, Pittet, Mikaël   +2 more
openaire   +5 more sources

Monocyte Subset Recruitment Marker Profile Is Inversely Associated With Blood ApoA1 Levels

Frontiers in Immunology, 2021
Dyslipidemia promotes development of the atherosclerotic plaques that characterise cardiovascular disease. Plaque progression requires the influx of monocytes into the vessel wall, but whether dyslipidemia is associated with an increased potential of ...
Vyoma K. Patel, Vyoma K. Patel, Helen Williams, Helen Williams, Stephen C. H. Li, Stephen C. H. Li, John P. Fletcher, John P. Fletcher, Heather J. Medbury, Heather J. Medbury   +9 more
doaj   +1 more source

Elevated circulating monocytes and monocyte activation in COVID-19 convalescent individuals

Frontiers in Immunology, 2023
BackgroundMonocytes and macrophages play a pivotal role in inflammation during acute SARS-CoV-2 infection. However, their contribution to the development of post-acute sequelae of SARS-CoV-2 infection (PASC) are not fully elucidated.MethodsA cross ...
Juwon Park, Juwon Park, Logan S. Dean, Logan S. Dean, Boonyanudh Jiyarom, Louie Mar Gangcuangco, Louie Mar Gangcuangco, Parthav Shah, Parthav Shah, Thomas Awamura, Lauren L. Ching, Vivek R. Nerurkar, Dominic C. Chow, Fritzie Igno, Cecilia M. Shikuma, Cecilia M. Shikuma, Cecilia M. Shikuma, Gehan Devendra, Gehan Devendra   +18 more
doaj   +1 more source

Differential expression of CCR2 and CX3CR1 on CD16+ monocyte subsets is associated with asthma severity

Allergy, Asthma & Clinical Immunology, 2019
Background Monocytes play an important role in immune and inflammatory diseases and monocyte subsets are predictors of disease in certain conditions. Expression of the chemokine receptors, CCR2 and CX3CR1 on monocyte subsets relates to their function and
Reem Al-Rashoudi, Gillian Moir, Mohamed S. Al-Hajjaj, Monther M. Al-Alwan, Heather M. Wilson, Isabel J. Crane   +5 more
doaj   +1 more source

The tissue factor expression on CD14++CD16-monocytes is a new markers in the Chinese Han older adult population with sepsis: A prospective study

Experimental Gerontology, 2023
Objective: To investigate the tissue factor (TF) expression on different subsets of monocyte and tissue factor secretion of peripheral blood and evaluate their association with the prognosis of sepsis in the Chinese older adult population.
Qian Gao, Li Yang, Fei Teng, Xiao-Yan Cheng, Shu-Bin Guo   +4 more
doaj   +1 more source

Targeting a Monocyte Subset to Reduce Inflammation [PDF]

Circulation Research, 2012
### Therapeutic siRNA Silencing in Inflammatory Monocytes in Mice Leuschner et al Nat Biotech . 2011;29:1005–1010. R ecently in Nature Biotechnology , Leuschner et al1 described an elegant method of limiting the recruitment of a proinflammatory subset of monocytes in mouse models of inflammation.
openaire   +2 more sources

Monocyte Subsets in Schistosomiasis Patients with Periportal Fibrosis [PDF]

Mediators of Inflammation, 2014
A major issue withSchistosoma mansoniinfection is the development of periportal fibrosis, which is predominantly caused by the host immune response to egg antigens. Experimental studies have pointed to the participation of monocytes in the pathogenesis of liver fibrosis.
Jamille Souza Fernandes, Maria Ilma Araujo, Diego Mota Lopes, Robson da Paixão de Souza, Edgar M. Carvalho, Luciana Santos Cardoso   +5 more
openaire   +3 more sources

Treponemapallidum Dysregulates Monocytes and Promotes the Expression of IL-1β and Migration in Monocytes Through the mTOR Signaling Pathway

Frontiers in Cellular and Infection Microbiology, 2020
Monocytes are widely involved in the body’s defense response, and abnormally regulated monocyte subsets are closely related to the pathogenesis of various diseases.
Wen-Na Liu, Wen-Na Liu, Xiao-Yong Jiang, Yan-Zhu Xu, Xiao-Han Sun, Kai-Xuan Wu, Xin-Lin Hu, Yong Lin, Li-Rong Lin, Man-Li Tong, Li-Li Liu   +10 more
doaj   +1 more source

Multicohort Analysis Identifies Monocyte Gene Signatures to Accurately Monitor Subset-Specific Changes in Human Diseases

Frontiers in Immunology, 2021
Monocytes are crucial regulators of inflammation, and are characterized by three distinct subsets in humans, of which classical and non-classical are the most abundant.
Francesco Vallania, Francesco Vallania, Liron Zisman, Liron Zisman, Liron Zisman, Claudia Macaubas, Shu-Chen Hung, Narendiran Rajasekaran, Sonia Mason, Jonathan Graf, Mary Nakamura, Elizabeth D. Mellins, Purvesh Khatri, Purvesh Khatri   +13 more
doaj   +1 more source