Results 41 to 50 of about 71,540 (227)

Expression of M2-associated molecules in circulating monocyte subsets in fertile non-pregnant women and pregnant women with uncomplicated pregnancy

Медицинская иммунология, 2022
In humans circulating monocytes include classical (CD14++CD16- ), intermediate (CD14++CD16+) and non-classical/alternative (CD14+CD16++) monocytes, which in turn can be activated via the classical or alternative pathway.
E. Ya. Shevela, N. G. Bukhtueva, M. A. Tikhonova, O. Yu. Leplina, N. M. Pasman, E. R. Chernykh   +5 more
doaj   +1 more source

Expression of CD163 and HLA-DR molecules on the monocytes in chronic lymphocytic leukemia patients

Folia Histochemica et Cytobiologica, 2020
INTRODUCTION: Human peripheral blood monocytes are the part of the leukemia microenvironment. We examined three monocyte subgroups: classical (CD14++CD16–), intermediate (CD14++CD16+) and non-classical (CD14+CD16++) monocytes. As these subpopulations can
Wioleta Kowalska
doaj   +1 more source

The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence [PDF]

Cell Death & Disease, 2018
AbstractHuman primary monocytes comprise a heterogeneous population that can be classified into three subsets based on CD14 and CD16 expression: classical (CD14high/CD16−), intermediate (CD14high/CD16+), and non-classical (CD14low/CD16+). The non-classical monocytes are the most pro-inflammatory in response to TLR stimulation in vitro, yet they express
Siew-Min Ong, Eva Hadadi, Truong-Minh Dang, Wei-Hseun Yeap, Crystal Tze-Ying Tan, Tze-Pin Ng, Anis Larbi, Siew-Cheng Wong   +7 more
openaire   +2 more sources

Monocyte Phenotypes and Physical Activity in Patients with Carotid Atherosclerosis

Antioxidants, 2022
Atherosclerosis is associated with low-grade inflammation involving circulating monocytes. It has been shown that the levels of intermediate pro-inflammatory monocytes are associated with cardiovascular mortality and risk of ischemic stroke.
Mathilde Mura, Michèle Weiss-Gayet, Nellie Della-Schiava, Erica Chirico, Patrick Lermusiaux, Marie Chambion-Diaz, Camille Faes, Anaelle Boreau, Bénédicte Chazaud, Antoine Millon, Vincent Pialoux   +10 more
doaj   +1 more source

In vitro Phenotype Induction of Circulating Monocytes: CD16 and CD163 Analysis

Journal of Inflammation Research, 2021
Claudio Karsulovic,1,2 Fabian Tempio,3,4 Mercedes Lopez,3,4 Julia Guerrero,1 Annelise Goecke1,2 1Laboratorio de Inmunomodulación Neuroendocrina, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile ...
Karsulovic C, Tempio F, Lopez M, Guerrero J, Goecke A   +4 more
doaj  

Non-Classical monocytes display inflammatory features: Validation in Sepsis and Systemic Lupus Erythematous. [PDF]

Sci Rep, 2015
AbstractGiven the importance of monocytes in pathogenesis of infectious and other inflammatory disorders, delineating functional and phenotypic characterization of monocyte subsets has emerged as a critical requirement. Although human monocytes have been subdivided into three different populations based on surface expression of CD14 and CD16, published
Mukherjee R, Kanti Barman P, Kumar Thatoi P, Tripathy R, Kumar Das B, Ravindran B.   +5 more
europepmc   +4 more sources

Interleukin-10 and non-classical monocytes as biomarkers of ischemic cardiomyopathy

Patologiya krovoobrashcheniya i kardiokhirurgiya, 2020
Background. Chronic heart failure frequently occurs against the background of ischemic heart disease (IHD), and has also been associated with the diagnosis of ischemic cardiomyopathy (ICMP). While there are significant commonalities with respect to underlying mechanisms, it would be most important to identify differential diagnostic markers to ...
V. Shipulin, S. Chumakova, D. Pogonchenkova, O. Urazova, M. Vins, A. Pryakhin, V. Novickiy   +6 more
openaire   +2 more sources

P083/O23 Novel subclass of non-classical monocytes are critical for inflammation [PDF]

Annals of the Rheumatic Diseases, 2019
Career situation of first and presenting author Post-doctoral fellow. Introduction Monocytes in mice are distinguishable by expression of Ly6c. Ly6chi (classical) monocytes are associated with pro-inflammatory responses, while Lyc6lo (non-classical) are involved in patrolling endothelial membranes.
AB Montgomery, PJ Homan, D Winter, HR Perlman   +3 more
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The Association of Lipoprotein(a) and Circulating Monocyte Subsets with Severe Coronary Atherosclerosis

Journal of Cardiovascular Development and Disease, 2021
Background and aims: Chronic inflammation associated with the uncontrolled activation of innate and acquired immunity plays a fundamental role in all stages of atherogenesis.
Olga I. Afanasieva, Anastasya Yu. Filatova, Tatiana I. Arefieva, Elena A. Klesareva, Alexandra V. Tyurina, Natalia V. Radyukhina, Marat V. Ezhov, Sergei N. Pokrovsky   +7 more
doaj   +1 more source