Results 11 to 20 of about 948,768 (269)

ADAM17-Mediated Reduction in CD14++CD16+ Monocytes ex vivo and Reduction in Intermediate Monocytes With Immune Paresis in Acute Pancreatitis and Acute Alcoholic Hepatitis [PDF]

Frontiers in Immunology, 2019
Impaired immune responses and increased susceptibility to infection characterize acute inflammatory conditions such as pancreatitis and alcoholic hepatitis and are major causes of morbidity and mortality.
Kathryn Waller, Charlotte James, Anja de Jong, Laura Blackmore, Yun Ma, Andrew Stagg, David Kelsell, Michael O'Dwyer, Robert Hutchins, William Alazawi   +9 more
doaj   +3 more sources

MicroRNA profiling of human intermediate monocytes

Immunobiology, 2017
Among the three human monocyte subsets, intermediate CD14++CD16+ monocytes have been characterized as particularly proinflammatory cells in experimental studies and as potential biomarkers of cardiovascular risk in clinical cohorts. To further substantiate the distinct role of intermediate monocytes within human monocyte heterogeneity, we assessed ...
Zawada, A.M., Zhang, L., Emrich, I.E., Rogacev, K.S., Krezdorn, N., Rotter, B., Fliser, D., Devaux, Y., Ziegler-Heitbrock, L., Heine, G.H.   +9 more
openaire   +4 more sources

Reprint of: MicroRNA profiling of human intermediate monocytes

Immunobiology, 2017
Among the three human monocyte subsets, intermediate CD14++CD16+ monocytes have been characterized as particularly proinflammatory cells in experimental studies and as potential biomarkers of cardiovascular risk in clinical cohorts. To further substantiate the distinct role of intermediate monocytes within human monocyte heterogeneity, we assessed ...
Zawada, A.M., Zhang, L., Emrich, I.E., Rogacev, K.S., Krezdorn, N., Rotter, B., Fliser, D., Devaux, Y., Ziegler-Heitbrock, L., Heine, G.H.   +9 more
openaire   +4 more sources

Corrigendum: Higher proportion of non-classical and intermediate monocytes in newly diagnosed multiple myeloma patients in Egypt: A possible prognostic marker [PDF]

African Journal of Laboratory Medicine, 2022
No abstract available.
Asmaa M. Zahran, Hanaa Nafady-Hego, Sawsan M. Moeen, Hanan A. Eltyb, Mohammed M. Wahman, Asmaa M. Nafady   +5 more
doaj   +2 more sources

An Allosteric Shift in CD11c Affinity Activates a Proatherogenic State in Arrested Intermediate Monocytes. [PDF]

J Immunol, 2020
Abstract Intermediate monocytes (iMo; CD14+CD16+) increase in number in the circulation of patients with unstable coronary artery disease (CAD), and their recruitment to inflamed arteries is implicated in events leading to mortality following MI. Monocyte recruitment to inflamed coronary arteries is initiated by high affinity β2-integrin
Hernandez AA, Foster GA, Soderberg SR, Fernandez A, Reynolds MB, Orser MK, Bailey KA, Rogers JH, Singh GD, Wu H, Passerini AG, Simon SI.   +11 more
europepmc   +6 more sources

Intermediate Monocytes and Cytokine Production Associated With Severe Forms of Chagas Disease. [PDF]

Front Immunol, 2019
يتم تصنيف الخلايا الأحادية وفقًا لتعبير CD14 و CD16 إلى كلاسيكية (تعويضية) ومتوسطة (التهابية) وغير كلاسيكية. قيمت هذه الدراسة تواتر الخلايا الأحادية والعلاقة بين النسب المئوية للمجموعات الفرعية من الخلايا الأحادية ومستويات سيتوكينات الدم لدى مرضى شاغاس الكولومبيين بأشكال سريرية مختلفة.
Gómez-Olarte S, Bolaños NI, Echeverry M, Rodríguez AN, Cuéllar A, Puerta CJ, Mariño A, González JM.   +7 more
europepmc   +6 more sources

IL-1β Production by Intermediate Monocytes Is Associated with Immunopathology in Cutaneous Leishmaniasis. [PDF]

J Invest Dermatol, 2018
Cutaneous leishmaniasis due to Leishmania braziliensis infection is an inflammatory disease in which skin ulcer development is associated with mononuclear cell infiltrate and high levels of inflammatory cytokine production. Recently, NLRP3 inflammasome activation and IL-1β production have been associated with increased pathology in murine cutaneous ...
Santos D, Campos TM, Saldanha M, Oliveira SC, Nascimento M, Zamboni DS, Machado PR, Arruda S, Scott P, Carvalho EM, Carvalho LP.   +10 more
europepmc   +4 more sources

Classical and intermediate monocytes scavenge non-transferrin-bound iron and damaged erythrocytes. [PDF]

JCI Insight, 2019
Myelomonocytic cells are critically involved in iron turnover as aged RBC recyclers. Human monocytes are divided in 3 subpopulations of classical, intermediate, and nonclassical cells, differing in inflammatory and migratory phenotype. Their functions in iron homeostasis are, however, unclear. Here, we asked whether the functional diversity of monocyte
Haschka D, Petzer V, Kocher F, Tschurtschenthaler C, Schaefer B, Seifert M, Sopper S, Sonnweber T, Feistritzer C, Arvedson TL, Zoller H, Stauder R, Theurl I, Weiss G, Tymoszuk P.   +14 more
europepmc   +4 more sources

Intermediate and nonclassical monocytes show heterogeneity in patients with different types of acute coronary syndrome [PDF]

Cytometry Part A, 2017
AbstractThis study was performed to gain further insight in the heterogeneity of monocytes in the different categories of acute coronary syndrome (ACS), especially between patients with unstable angina pectoris, ST‐elevation myocardial infarction (STEMI), and non‐ST‐elevation myocardial infarction (NSTEMI).
Leers, Math P. G., Stockem, Chantal, Ackermans, Dianne, Loeffen, Rinske, ten Cate, Hugo, Kragten, Johannes A., Jie, Kon-Siong G.   +6 more
openaire   +4 more sources

Single-cell transcriptomic landscape reveals the role of intermediate monocytes in aneurysmal subarachnoid hemorrhage. [PDF]

Front Cell Dev Biol
ObjectiveNeuroinflammation is associated with brain injury and poor outcomes after aneurysmal subarachnoid hemorrhage (SAH). In this study, we performed single-cell RNA sequencing (scRNA-seq) to analyze monocytes and explore the mechanisms of neuroinflammation after SAH.MethodsWe recruited two male patients with SAH and collected paired cerebrospinal ...
Meng N, Su Y, Ye Z, Xie X, Liu Y, Qin C.
europepmc   +4 more sources