Results 51 to 60 of about 948,768 (269)

Lung Macrophages Serve as Obligatory Intermediate between Blood Monocytes and Alveolar Macrophages [PDF]

The Journal of Immunology, 2007
Abstract Alveolar macrophages are a unique type of mononuclear phagocytes that populate the external surface of the lung cavity. Early studies have suggested that alveolar macrophages originate from tissue-resident, local precursors, whereas others reported their derivation from blood-borne cells.
Limor, Landsman, Steffen, Jung
openaire   +2 more sources

Quantitative whole-cell MALDI-TOF MS fingerprints distinguishes human monocyte sub-populations activated by distinct microbial ligands [PDF]

, 2015
Conventionally, human monocyte sub-populations are classified according to surface marker expression into classical (CD14(++)CD16(-)), intermediate (CD14(++)CD16(+)) and non-classical (CD14(+)CD16(++)) lineages. The involvement of non-classical monocytes,
Brunisholz, René, Vogel, Guido, Daubenberger, Claudia, Patricia Otieno, René Brunisholz, Pflüger, Valentin, Portevin, Damien, Valentin Pflüger, Otieno, Patricia, Damien Portevin, Claudia Daubenberger, Guido Vogel   +11 more
core   +1 more source

Frequency of intermediate and non-classical monocytes to the total monocytes by HIV (H) and CVD(C) status.

, 2023
Frequency of intermediate and non-classical monocytes to the total monocytes by HIV (H) and CVD(C) status.
Karin Mueller (579839), Joan W. Berman (10860768), Klaus Ley (8593), Mardge H. Cohen (7923182), Igho Ofotokun (4059922), Stephen Gange (15674986), Tao Wang (12008), Kathryn Anastos (119435), Alan L. Landay (7919387), Phyllis C. Tien (7923128), Jason M. Lazar (10002157), Howard N. Hodis (9338345), David B. Hanna (10649576), Yanal Ghosheh (3404441), Sonya L. Heath (11605483), Qibin Qi (172143), Erik Ehinger (13558375), Juan Lin (171491), Russell P. Tracy (7300421), Wendy J. Mack (7923125), Chenglong Liu (317596), Robert C. Kaplan (7699334)   +21 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes [PDF]

, 2012
Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs.
Lorin, V, Tangy, Frédéric, Vabret, Astrid, Vidalain, Pierre-Olivier, Tangy, F, Escriou, Nicolas, Millet, J, Escriou, N, Law, H, Albert, ML, Millet, Jean, K., Nal, B, Law, Helen, Albert, Matthew L, Vabret, A, Nal, Béatrice, Lorin, Valérie, Vidalain, PO, Mesel-Lemoine, Mariana   +18 more
core   +1 more source

Monocyte subsets display age-dependent alterations at fasting and undergo non-age-dependent changes following consumption of a meal

Immunity & Ageing, 2022
Background Monocytes are a heterogenous population of immune cells whose subsets and functions become substantially dysregulated with advanced age. Although much of our current understanding of the age-related changes in monocytes is derived from fasting
Ryan G. Snodgrass, Xiaowen Jiang, Charles B. Stephensen   +2 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Fcγ receptor expression on monocytes and association with etanercept efficacy in rheumatoid arthritis: a prospective cohort study

Frontiers in Pharmacology
BackgroundTo investigate whether Fcγ receptors (FcγRs) expression on peripheral blood monocytes predicts clinical response to etanercept in rheumatoid arthritis (RA).MethodsIn this prospective cohort study, FcγRs expression on peripheral blood monocyte ...
Tongxin Wang, Hanchao Li, Li Zhu, Ying Pan, Jing Luo, Jing Zhang, Nan Hu, Lan He, Yining Sun   +8 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source