Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes [PDF]
EMBO Molecular Medicine, 2013 We used a novel approach of cytostatically induced leucocyte depletion and subsequent reconstitution with leucocytes deprived of classical (inflammatory/Gr1hi) or non‐classical (resident/Gr1lo) monocytes to dissect their differential role in ...
Oliver Soehnlein +15 more
doaj +3 more sources
Classical monocytes from patients with pancreatic ductal adenocarcinoma exhibit a significantly altered transcriptome profile compared with healthy volunteers [PDF]
, 2014 The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorPancreatic Ductal Adenocarcinoma (PDAC) affects approximately 8000 people every ...
Cook, Jenny Anne
core +4 more sources
Diminished Non-Classical Monocytes in the Blood Associate with Disease Severity in Alcoholic Hepatitis. [PDF]
Clin Exp Gastroenterol, 2021 Elisabeth Busk Rasmussen,1 Lotte Lindgreen Eriksen,2 Stinne Ravn Greisen,1 Anne Louise Hansen,1 Mikkel Carstensen,1 Thomas Damgaard Sandahl,2 Sidsel Støy,2 Tue Wenzel Kragstrup1,3 1Department of Biomedicine, Aarhus University, Aarhus, Denmark ...
Rasmussen EB +7 more
europepmc +2 more sources
Interferon as a macrophage activating factor. I. Enhancement of cytotoxicity by fresh and matured human monocytes in the absence of other soluble signals [PDF]
, 1983 The cytolytic activity ofhuman peripheral blood monocytes in vitro against K-562 human leukaemic target cells was stimulated by human fibroblast (fi-) and leucocyte (a-) interferon (IFN). Stimulation was by up to several times the corresponding control
Virelizier, JL, Dean, RT
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CD56 and Tim-3 molecule expression in different monocyte subsets in physiological pregnancy
Медицинская иммунология, 2023 Monocytes play an important role in the systemic immune defense against pathogens and maintaining physiological pregnancy. During pregnancy peripheral monocytes migrate into the decidua and form the pool of decidual macrophages which participate in the ...
E. G. Orlova, O. A. Loginova
doaj +1 more source
Phenotype, function, and differentiation potential of human monocyte subsets. [PDF]
PLoS ONE, 2017 Human monocytes have been grouped into classical (CD14++CD16-), non-classical (CD14dimCD16++), and intermediate (CD14++CD16+) subsets. Documentation of normal function and variation in this complement of subtypes, particularly their differentiation ...
Lisa B Boyette +9 more
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Frontiers in Physiology, 2023 Introduction: Although it is broadly known that monocyte recruitment is involved in atherosclerosis development and that, in accordance with the microenvironment, these cells can be modulated into three well-known subpopulations: Classical (CD14++CD16−),
Daniel Carneiro de Carvalho +8 more
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Blood monocytes and their subsets: established features and open questions
Frontiers in Immunology, 2015 In contrast to the past reliance on morphology the identification and enumeration of blood monocytes is nowadays done with monoclonal antibodies and flow cytometry and this allows for subdivision into classical, intermediate and non-classical monocytes ...
Loems eZiegler-Heitbrock
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Hepatic Ly6CLo Non-Classical Monocytes Have Increased Nr4a1 (Nur77) in Murine Biliary Atresia. [PDF]
J Clin Med, 2022 Biliary atresia (BA) is a rapidly progressive perinatal inflammatory disease, resulting in liver failure. Hepatic Ly6CLo non-classical monocytes promote the resolution of perinatal liver inflammation during rhesus rotavirus-mediated (RRV) BA in mice.
Mohamedaly S +6 more
europepmc +2 more sources
Nr4a1-dependent non-classical monocytes are important for macrophage-mediated wound healing in the large intestine. [PDF]
Front Immunol, 2022 INTRODUCTION: Macrophages play an important role in intestinal wound healing. However, the trajectories from circulating monocytes to gut macrophages are incompletely understood.
Heidbreder K +7 more
europepmc +2 more sources