Results 171 to 180 of about 948,768 (269)

Chronic HBV Infection Disrupts CCL5‐Secreting cNK Cells and Attenuates Liver Accumulation and Activation of DCs and HBV‐Specific T Cells

Advanced Science, EarlyView.
ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang, Yucan Wang, Yating Yu, Jing Wu, Cuiping Bao, Zixuan Wang, Qiuju Han, Zhigang Tian, Jian Zhang, Huajun Zhao   +9 more
wiley   +1 more source

Programmable Encapsulation Enables On‐Demand Proliferation of Therapeutic Bacteria for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang, Ao Peng, Shuaiqiang Li, Yaning Huang, Jian Yan, Leyuan Wang, Zhihui Zhu, Fei‐Long Liu, Erbao Bian, Yang Liu, Dasheng Tian, Fenghe Li, Qi Liu   +12 more
wiley   +1 more source

PD-1/PD-L1-CXCR3 Coexpression and CXCR3 on Intermediate Monocytes Predict Fibrosis, Leukemic Transformation, and Survival in Egyptian Philadelphia-Negative Myeloproliferative Neoplasms. [PDF]

Clin Med Insights Oncol
Sherief DE, Elmezien RA, Nosair N, Othman AA, Sadaka E, Elgamal R.   +5 more
europepmc   +1 more source

Elevated circulating CD14⁺⁺CD16⁺ intermediate monocytes are independently associated with extracardiac complications after cardiac surgery. [PDF]

Sci Rep, 2020
Mossanen JC, Jansen TU, Pracht J, Liepelt A, Buendgens L, Stoppe C, Goetzenich A, Simon TP, Autschbach R, Marx G, Tacke F.   +10 more
europepmc   +1 more source

Immediate Growth Control in Response to Boiling Histotripsy is Prognostic for Intratumoral Immune Activation

Advanced Science, EarlyView.
Boiling Histrotripsy (BH), a mechanical form of focused ultrasound (FUS), allows for non‐invasive and non‐ionizing tissue destruction. Utilizing a BH treatment protocol that yielded bifurcating primary tumor growth responses, we found that immediate BH‐induced tumor growth control identifies tumors with acute reductions in antigen‐presenting cells (APC)
Lydia E. Kitelinger, Matthew R. DeWitt, Carly M. Van Wagoner, Claire A. Conarroe, Charles C. Funk, Aaron B. Streit, AeRyon Kim, Richard J. Price, Timothy N. J. Bullock   +8 more
wiley   +1 more source

Role of monocytes in cancer progression (an in vitro approach)

reservedMacrophages, predominantly derived from highly plastic circulating monocytes, constitute one of the first line of defense against exogenous and endogenous threats.
DAL ZOVO, ERICA
core  

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

Advanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan, Zifan Pei, Jie Wu, Nan Jiang, Qian Li, Yuqi Yang, Jie Cao, Yechen Huang, Shumin Sun, Qialu Du, Zhicheng Liu, Lin Zhang, Fei Gong, Jinhua Zhou, Liang Cheng   +14 more
wiley   +1 more source

Circulating CD16-Positive Monocyte-like Myeloid-Derived Suppressor Cells and Intermediate Monocytes Associated with Clinical and Immunological Complications in Pars Planitis Patients. [PDF]

Cells
Kosmaczewska A, Przeździecka-Dołyk J, Ciszak L, Rojek-Gajda Z, Frydecka I, Turno-Kręcicka A, Misiuk-Hojło M, Pawlak E.   +7 more
europepmc   +1 more source

Intermediate monocytes expansion and homing markers expression in COVID-19 patients associate with kidney dysfunction

, 2022
Dentone C, Fenoglio D, Parodi A, Altosole T, Biagio A, Bozzano F, Nasi G, Vena A, Fabbi M, Ferrera F, Bruzzone B, Giacomini M, Giacobbe DR, Pelosi P, De Maria A, Bassetti M, De Palma R, Filaci G.   +17 more
europepmc   +1 more source