Introduction There is currently only one approved medication effective at improving walking distance in people with intermittent claudication. Preclinical data suggest that the β3-adrenergic receptor agonist (mirabegron) could be repurposed to treat ...
Clara Chow +15 more
doaj +1 more source
A review of the potential local mechanisms by which exercise improves functional outcomes in intermittent claudication [PDF]
© 2016 Elsevier Inc. All rights reserved. Background Intermittent claudication (IC) is a common condition which is associated with significant quality of life limitation.
Cayton, Thomas +6 more
core +1 more source
A Rare Case of Intermittent Claudication Associated with Impaired Arterial Vasodilation
Exercise-related intermittent claudication is marked by reduced blood flow to extremities caused by either stenosis or impaired vascular function. Although intermittent claudication is common in the elderly, it rarely occurs in the young and middle-aged ...
J. J. Posthuma +6 more
doaj +1 more source
BackgroundIntermittent claudication (IC) is the most common symptom of peripheral arterial disease and is generally treated conservatively due to limited prognostic evidence to support early revascularisation in the individual patient.
Anabelle Mizzi +3 more
semanticscholar +1 more source
Background Type 2 diabetes mellitus is a risk factor for lower extremity arterial disease. Cilostazol expresses antiplatelet, anti‐inflammatory, and vasodilator actions and improves the claudication intermittent symptoms. We investigated the efficacy and
Kallirroi Kalantzi +36 more
doaj +1 more source
Crossroads between peripheral atherosclerosis, western-type diet and skeletal muscle pathophysiology: emphasis on apolipoprotein E deficiency and peripheral arterial disease [PDF]
Atherosclerosis is a chronic inflammatory process that, in the presence of hyperlipidaemia, promotes the formation of atheromatous plaques in large vessels of the cardiovascular system.
Matsakas, Antonios, Sfyri, Peggy
core +1 more source
Objective: To determine the effect of intermittent pneumatic foot and calf compression on popliteal artery mean systolic blood flow in patients with intermittent claudication. The secondary objective was to determine the change in blood flow with posture.
Daphne Anthonysamy +2 more
doaj +1 more source
Physical Activity Levels in Peripheral Artery Disease Patients [PDF]
BACKGROUND: Increases in daily physical activity levels is recommended for patients with peripheral artery disease (PAD). However, despite this recommendation, little is known about the physical activity patterns of PAD patients.
Correia, Marilia de Almeida +9 more
core +2 more sources
Long-term outcomes of a randomized clinical trial of supervised exercise, percutaneous transluminal angioplasty or combined treatment for patients with intermittent claudication due to femoropopliteal disease [PDF]
Background: To compare the long-term outcomes of angioplasty (PTA), supervised exercise (SEP) and combined treatment (PTA+SEP) in patients with intermittent claudication (IC) due to femoropopliteal disease. Methods: Patients recruited to PTA, SEP and PTA+
Carradice, Daniel +6 more
core +2 more sources
Atherectomy With Multimodal Embolic Protection for Severely Calcified Femoropopliteal Lesions
ABSTRACT Severe calcification in femoropopliteal lesions remains a clinical challenge to achieve both the technical and long‐term success in endovascular therapy. Although atherectomy is an effective treatment for calcified lesions, it is associated with the risk of distal embolization, even with the use of embolic protection devices (EPDs), and ...
Daichi Yoshii +3 more
wiley +1 more source

