Results 111 to 120 of about 38,089 (218)

Full‐Spectrum Medicinal Cannabis Plant Extract 0.08% THC (NTI164) Improves Symptoms of Rett Syndrome: An Open‐Label Study

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim The aim of this Phase I/II open‐label study was to assess the safety and efficacy of NTI164, a novel full‐spectrum medicinal cannabis plant extract 0.08% Δ‐9‐tetrahydrocannabinol (THC), in Rett syndrome (RTT). Methods Eleven female participants (5–16 years) with a pathogenic variant in the MECP2 gene were recruited to this study, receiving
B. A. Keating   +7 more
wiley   +1 more source

Clinician Perspectives of Oxygen Control in Children With Bronchopulmonary Dysplasia at Home: An International Survey of Clinicians From 44 Countries

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Bronchopulmonary dysplasia (BPD) is the most common complication of preterm birth and may lead to difficulties with oxygen control even at home. How oxygenation is managed outside the hospital and in high and low resourced settings is unclear. Aims To determine clinician perspectives for managing oxygenation after hospital discharge
Thy A. N. Pham   +23 more
wiley   +1 more source

Lung Vascular Remodeling and Oxidative Damage Induced by Chronic Intermittent Hypoxia. [PDF]

open access: yesInt J Mol Sci
Figueroa EG   +7 more
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger   +5 more
wiley   +1 more source

The Role of Oxidative Stress in Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon   +3 more
wiley   +1 more source

Time-restricted eating improves intermittent hypoxia-induced dysglycemia. [PDF]

open access: yesSleep
Afif CP   +9 more
europepmc   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet   +8 more
wiley   +1 more source

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