Results 1 to 10 of about 17,576 (144)

Biomechanical and structural responses of the aorta to intermittent hypobaric hypoxia in a rat model. [PDF]

Sci Rep, 2022
High altitude hypoxia is a condition experienced by diverse populations worldwide. In addition, several jobs require working shifts where workers are exposed to repetitive cycles of hypobaric hypoxia and normobaric normoxia. Currently, few is known about
Utrera A, Navarrete Á, González-Candia A, García-Herrera C, Herrera EA.   +4 more
europepmc   +7 more sources

Cardioprotective Antioxidant and Anti-Inflammatory Mechanisms Induced by Intermittent Hypobaric Hypoxia. [PDF]

Antioxidants (Basel), 2022
More than 80 million people live and work (in a chronic or intermittent form) above 2500 masl, and 35 million live in the Andean Mountains. Furthermore, in Chile, it is estimated that 100,000 people work in high-altitude shifts, where stays in the ...
González-Candia A, Candia AA, Paz A, Mobarec F, Urbina-Varela R, Campo AD, Herrera EA, Castillo RL.   +7 more
europepmc   +6 more sources

Chronic Intermittent Hypobaric Hypoxia Enhances Bone Fracture Healing. [PDF]

Front Endocrinol (Lausanne), 2020
The effect of chronic intermittent hypobaric hypoxia (CIHH) on bone fracture healing is not elucidated. The present study aimed to investigate the role of CIHH on bone fracture healing and the mechanism. The Sprague-Dawley rats were randomly divided into
Zhang L, Jin L, Guo J, Bao K, Hu J, Zhang Y, Hou Z, Zhang L.   +7 more
europepmc   +6 more sources

Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice. [PDF]

J Neurosci, 2023
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by persistent deficits in social communication and stereotyped behaviors.
Pan YD, Zhang Y, Zheng WY, Zhu MZ, Li HY, Ouyang WJ, Wen QQ, Zhu XH.   +7 more
europepmc   +4 more sources

Preconditioning With Intermittent Hypobaric Hypoxia Attenuates Stroke Damage and Modulates Endocytosis in Residual Neurons. [PDF]

Front Neurol, 2021
Background: Moderate hypobaric hypoxia induces cerebral ischemic tolerance. We investigated the optimal method for applying hypobaric hypoxia preconditioning at 5,000 m to ischemic brain tissue and combined it with proteomics to determine the mechanisms ...
Wan Y, Huang L, Liu Y, Ji W, Li C, Ge RL.   +5 more
europepmc   +3 more sources

Astaxanthin Supplementation Effects in Right Ventricle of Rats Exposed to Chronic Intermittent Hypobaric Hypoxia. [PDF]

Antioxidants (Basel)
In Chile, individuals are commonly exposed to high altitude due to the work shift system, involving days of exposure to high altitude followed by days at sea level over the long term, which can result in chronic intermittent hypobaric hypoxia (CIHH ...
Pena E, El Alam S, Gonzalez C, Cortés I, Aguilera D, Flores K, Arriaza K.   +6 more
europepmc   +3 more sources

The Impact of Intermittent Hypobaric Hypoxia Exposures on Triacylglycerol Synthesis in Rat Liver. [PDF]

Rep Biochem Mol Biol, 2021
Background In a hypoxic state, fatty acid breakdown reaction may be inhibited due to a lack of oxygen. It is likely that the fatty acids will be stored as triacylglycerol.
Dewi S, Yulhasri Y, Mulyawan W.
europepmc   +5 more sources

Intermittent Hypobaric Hypoxia Preconditioning Ameliorates Kidney Damage Compared to Acute Hypoxia

Hayati Journal of Biosciences
Many studies have reported that intermittent hypobaric hypoxia (IHH) can cause oxidative stress and tissue damage in the kidneys, which can lead to impaired kidney function.
Abdul Halim Sadikin, Sri Widia Azraki Jusman, Wawan Mulyawan, Ani Retno Prijanti   +3 more
doaj   +3 more sources

Body Composition, Microbiome and Physical Activity in Workers Under Intermittent Hypobaric Hypoxia. [PDF]

Nutrients
Background/Objectives: Intermittent hypobaric hypoxia (IHH) induces various physiological and metabolic adaptations. This study aimed to investigate the effects of a seven-day IHH exposure on nutritional status, body composition, gut microbiota, movement
Torres-Mejías J, Arriaza K, Mena F, Rivarola E, Paredes P, Ahmad H, López I, Soza D, Pino-Villalón JL, López-Espinoza MÁ, Duran-Agüero S, Merellano-Navarro E.   +11 more
europepmc   +4 more sources

Chronic intermittent hypobaric hypoxia attenuates root resorption following delayed tooth replantation by upregulating OPG/RANKL signaling pathway. [PDF]

BMC Oral Health
Background Tooth avulsion, a severe dental trauma prevalent among adolescents, is commonly treated with delayed replantation. However, this procedure is frequently complicated by root resorption, which can ultimately lead to tooth loss.
Jia L, Zhang L, Wang J, Zhang Y, Ma H, Du L, Lv B, Zhao Z, Ma H.   +8 more
europepmc   +3 more sources