Results 31 to 40 of about 17,595 (163)

Physiological and Biological Responses to Short-Term Intermittent Hypobaric Hypoxia Exposure: From Sports and Mountain Medicine to New Biomedical Applications. [PDF]

Front Physiol, 2018
In recent years, the altitude acclimatization responses elicited by short-term intermittent exposure to hypoxia have been subject to renewed attention. The main goal of short-term intermittent hypobaric hypoxia exposure programs was originally to improve
Viscor G, Torrella JR, Corral L, Ricart A, Javierre C, Pages T, Ventura JL.   +6 more
europepmc   +2 more sources

Chronic Intermittent Hypobaric Hypoxia Restores Hippocampus Function and Rescues Cognitive Impairments in Chronic Epileptic Rats via Wnt/β-catenin Signaling. [PDF]

Front Mol Neurosci, 2020
Epilepsy is a complex neurological disorder with frequent psychiatric, cognitive, and social comorbidities in addition to recurrent seizures. Cognitive impairment, one of the most common comorbidities, has severe adverse effects on quality of life ...
Sun C, Fu J, Qu Z, Jia L, Li D, Zhen J, Wang W.   +6 more
europepmc   +2 more sources

Protection of Pentoxifylline against Testis Injury Induced by Intermittent Hypobaric Hypoxia. [PDF]

Oxid Med Cell Longev, 2016
To investigate the effect of pentoxifylline (PTX) on spermatogenesis dysfunction induced by intermittent hypobaric hypoxia (IHH) and unveil the underlying mechanism, experimental animals were assigned to Control, IHH+Vehicle, and IHH+PTX groups and exposed to 4 cycles of 96 h of hypobaric hypoxia followed by 96 h of normobaric normoxia for 32 days. PTX
Yao C, Li G, Qian Y, Cai M, Yin H, Xiao L, Tang W, Guo F, Shi B.   +8 more
europepmc   +4 more sources

Implication of gut microbiota in the physiology of rats intermittently exposed to cold and hypobaric hypoxia.

PLoS ONE, 2020
This study examines the influence of intermittent exposure to cold, hypobaric hypoxia, and their combination, in gut microbiota and their metabolites in vivo, and explores their effects on the physiology of the host.
Sara Ramos-Romero, Garoa Santocildes, David Piñol-Piñol, Carles Rosés, Teresa Pagés, Mercè Hereu, Susana Amézqueta, Joan Ramon Torrella, Josep Lluís Torres, Ginés Viscor   +9 more
doaj   +6 more sources

Contractile Activity Is Necessary to Trigger Intermittent Hypobaric Hypoxia-Induced Fiber Size and Vascular Adaptations in Skeletal Muscle. [PDF]

Front Physiol, 2018
Altitude training has become increasingly popular in recent decades. Its central and peripheral effects are well-described; however, few studies have analyzed the effects of intermittent hypobaric hypoxia (IHH) alone on skeletal muscle ...
Rizo-Roca D, Bonet JB, Ínal B, Ríos-Kristjánsson JG, Pagès T, Viscor G, Torrella JR.   +6 more
europepmc   +2 more sources

Intermittent hypobaric hypoxia induces oxidative stress and vascular remodeling in rat pulmonary arteries

Jurnal Medik Veteriner
Flight crews frequently experience intermittent hypobaric hypoxia (IHH), which may trigger oxidative stress and vascular remodeling in the pulmonary arteries.
Sri Nurbowo Ardi, Muhammad Arza Putra, Dewi Sukmawati, Puspita Eka Wuyung, Wawan Mulyawan, Wardaya, Wiwien Heru Wiyono   +6 more
doaj   +2 more sources

Intermittent hypobaric hypoxia causes deleterious effects on the reproductive system in female rats.

Biomedicine & Pharmacotherapy, 2020
BACKGROUNDS Numerous studies have revealed that hypobaric hypoxia exposure elicited imbalance of homeostasis. However, the effects of intermittent hypobaric hypoxia (IHH) exposure on the female reproductive system have been rarely reported.
Weili Liu, L. Pu, Bing-nan Deng, Hongbao Xu, Zi-rou Wang, Tianhui Wang, R. Duan, Xinxing Wang, Zhao-li Chen   +8 more
semanticscholar   +3 more sources

Systematic review and meta-analysis of antioxidant treatment in patients with acute mountain sickness induced by high altitude exposure. [PDF]

Front Physiol
Acute Mountain Sickness (AMS) is a frequent condition triggered by exposure to hypobaric hypoxia at high altitude. Its pathophysiology involves endothelial dysfunction and oxidative stress, with elevated oxidative molecules identified as key contributors
Pena E, Del Río A, Flores S.
europepmc   +2 more sources

Neuroprotective Role of Intermittent Hypobaric Hypoxia in Unpredictable Chronic Mild Stress Induced Depression in Rats. [PDF]

PLoS One, 2016
Hypoxic exposure results in several pathophysiological conditions associated with nervous system, these include acute and chronic mountain sickness, loss of memory, and high altitude cerebral edema.
Kushwah N, Jain V, Deep S, Prasad D, Singh SB, Khan N.   +5 more
europepmc   +2 more sources

Intermittent hypobaric hypoxia applicability in myocardial infarction prevention and recovery [PDF]

Journal of Cellular and Molecular Medicine, 2012
AbstractIntermittent hypobaric hypoxia (IHH) has been the focus of important research in cardioprotection, and it has been associated with several mechanisms. Intermittent hypobaric hypoxia inhibits prolyl hydroxylases (PHD) activity, increasing the stabilization of hypoxia‐inducible factor‐1 (HIF‐1) and activating crucial adaptative genes. It has been
Sanchis Gomar F, Viña J, LIPPI, Giuseppe   +2 more
openaire   +3 more sources