Results 141 to 150 of about 38,089 (218)

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Chronic intermittent hypoxia reshapes circadian metabolic architecture in a model of sleep apnea. [PDF]

Sci Adv
Montellier E, Vial G, Bouyon S, Ashtiani KC, Abdelkarim S, Lemarie E, Boutin A, Kinouchi K, Baldi P, Pépin JL, Gaucher J.   +10 more
europepmc   +1 more source

Persistent Erythrocytosis in a Dog With a Spinal Sclerosing Paraganglioma

Veterinary Clinical Pathology, EarlyView.
ABSTRACT A 7‐year‐old, male, castrated, mixed‐breed dog presented with right pelvic limb lameness and pain on posturing to defecate that began 1.5 years prior to presentation. Radiographs taken 8 months prior to presentation showed a small lytic lesion of the L6 vertebral body, and CBCs showed a persistently increased hematocrit (HCT) for at least 2 ...
Samuel V. Neal, Samantha L. Sommer, Sarah Golconda, Eric T. Hostnik, Russell Sakacs, Janice Park, Ashley Potts, Ronaldo C. da Costa, Christopher Premanandan, Kara Corps, Sanggu Kim, Maxey L. Wellman   +11 more
wiley   +1 more source

Noninvasive diffuse optical monitoring of cerebral blood flow and oxygenation responses to intermittent hypoxia in neonatal rats. [PDF]

J Biomed Opt
Safavi P, Mohtasebi M, Azimul Haque C, Akbari F, Liu X, Yuan Y, Chen L, Chen L, Yu G.   +8 more
europepmc   +1 more source

Presumptive Acute Post‐Hypoxic Myoclonus Following Return of Spontaneous Circulation in a Cat and a Dog

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To describe the clinical presentation of presumptive acute post‐hypoxic myoclonus in a cat and a dog after cardiopulmonary arrest (CPA). In people, acute post‐hypoxic myoclonus is a transient focal, multifocal, or generalized rhythmic myoclonus that results from global hypoxic–ischemic brain injury and may be cortical or subcortical ...
Theofanis Liatis, Alison Robertson, Alberta De Stefani   +2 more
wiley   +1 more source

Chronic intermittent hypoxia exacerbates isoproterenol-induced cardiac hypertrophy and apoptosis. [PDF]

Front Cardiovasc Med
Zhang Y, Zhang M, Jiang H, Fang F.
europepmc   +1 more source

Optimizing cerebrovascular endothelial health through shear stress modulation

Experimental Physiology, EarlyView.
Abstract The endothelium plays a pivotal role in regulating cerebrovascular blood flow, and its dysfunction increases the risk of cerebrovascular disease. Endothelial shear stress, a primary mechanical stimulus for endothelial nitric oxide production, is a key modulator of vascular adaptation.
Erika Iwamoto, Rintaro Sakamoto, Darren P. Casey   +2 more
wiley   +1 more source

RNA-seq analysis unveils differential gene expression patterns following intermittent hypoxia in the mandibular condyles of growing male rats. [PDF]

Front Physiol
Jariyatheerawong K, Hosomichi J, Changsiripun C, Maeda H, Huang AC, Ono T.   +5 more
europepmc   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Telomere dysfunction is associated with exacerbated intermittent hypoxia-induced cognitive deficits and nerve damage. [PDF]

Front Aging Neurosci
Guo Y, Miao Y, Tan J, Zhao R, Jiang D, Zou M, Wang F, Zhang Q.   +7 more
europepmc   +1 more source