Results 51 to 60 of about 76,835 (291)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Bond strength and confinement in reinforced concrete

, 2022
The strength assessment of existing reinforced concrete structures is challenging when deterioration and detailing deficiencies are present. The anchorage of the internal steel reinforcement can be critical under particular confinement conditions of ...

core   +1 more source

Machine learning prediction of interfacial bond strength of FRP bars with different surface characteristics to concrete

Case Studies in Construction Materials
Fiber-reinforced polymer (FRP) bars have been implemented in civil infrastructures as internal reinforcement. The bond strength of FRP bars to concrete depends on the surface characteristics considerably.
Lingyu Tian, Luchen Wang, Guijun Xian
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Optimization of Wood-Plastic Composites by Response Surface Method

BioResources
To improve the material properties of wood-plastic composite, poplar fiber and polyethylene powder were used as the main components, a hot-press experiment was conducted using response surface methodology, and the relationship between processing ...
Feng Ji
doaj   +2 more sources

Evaluation of Bond Strength and Internal Adaptation Between the Dental Cavity and Adhesives Applied in One and Two Layers [PDF]

Operative Dentistry, 2010
SUMMARY This research evaluated the influence of the number of adhesive layers of three adhesive systems on microtensile bond strength (μTBS) to dentin and the internal adaptation between the dental structure and the resin composite restoration. Two cavities (C-factor=3) were made on the buccal surfaces of 30 bovine incisors.
Clarissa Grassi, Soares, Helena Glüer, Carracho, Ana Paula, Braun, Gilberto Antonio, Borges, Luciana Mayumi, Hirakata, Ana Maria, Spohr   +5 more
openaire   +2 more sources

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Investigation on the bond-slip behavior of recycled aggregate concrete-filled steel tube with studs.

PLoS ONE
This study investigates the influence of built-in studs on the bond behavior in recycled aggregate concrete-filled steel tube (RACFST) composite structures through push-out experiments.
Gehao Cai, Bing Sun, Sheng Zeng, Peng Yang, Jie Zhang   +4 more
doaj   +1 more source

Evaluation of the Bond-to-Concrete Properties of GFRP Rebars in Marine Environments

Infrastructures, 2018
Increased traffic in combination with growing environmental impacts have led to the accelerated degradation of built infrastructure. In reinforced concrete structures, the corrosion of steel reinforcement is the predominant cause of deterioration.
Alvaro Ruiz Emparanza, Francisco De Caso Y Basalo, Raphael Kampmann, Itziar Adarraga Usabiaga   +3 more
doaj   +1 more source