Results 101 to 110 of about 407,487 (268)

Early‐onset Alzheimer's disease shows a distinct neuropsychological profile and more aggressive trajectories of cognitive decline than late‐onset

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1962-1973, December 2022., 2022
Abstract Objectives Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cognitive function in a well characterized cohort of patients with a biomarker‐based diagnosis.
Adrià Tort‐Merino   +16 more
wiley   +1 more source

Thinking Styles Inventory: Psychometric features in college students from Buenos Aires

open access: yesInteracciones, 2019
Background: Thinking styles lead to describe how people use their abilities when they have to deal with problem solving situations. The Thinking Styles Inventory –TSI- is one of the most worldwide employed scales, developed to assess 13 thinking styles ...
Agustín Freiberg Hoffmann   +3 more
doaj   +1 more source

On the internal consistency of holographic dark energy models [PDF]

open access: yesJournal of Cosmology and Astroparticle Physics, 2008
8 pages, version to appear in ...
openaire   +3 more sources

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

open access: yesFEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang   +7 more
wiley   +1 more source

Recognizing early MRI signs (or their absence) is crucial in diagnosing metachromatic leukodystrophy

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1999-2009, December 2022., 2022
Abstract Objectives Metachromatic leukodystrophy (MLD) has characteristic white matter (WM) changes on brain MRI, which often trigger biochemical and genetic confirmation of the diagnosis. In early or pre‐symptomatic disease stages, these typical MRI changes might be absent, hampering early diagnosis.
Daphne H. Schoenmakers   +7 more
wiley   +1 more source

Construção de uma tarefa de leitura em voz alta de palavras: análise psicométrica dos itens The construction of a word reading aloud task: a psychometric item analysis report

open access: yesPsicologia: Reflexão e Crítica, 2012
O estudo descreve a análise dos itens que irão compor uma tarefa de leitura em voz alta de palavras isoladas. Um grupo de crianças do 2º ao 5º ano do Ensino Fundamental leu, por meio de microcomputadores, uma lista contendo 323 palavras de baixa ...
Patrícia Silva Lúcio   +3 more
doaj  

Internal Consistency and Self-Feedback in Large Language Models: A Survey [PDF]

open access: yesarXiv
Large language models (LLMs) often exhibit deficient reasoning or generate hallucinations. To address these, studies prefixed with "Self-" such as Self-Consistency, Self-Improve, and Self-Refine have been initiated. They share a commonality: involving LLMs evaluating and updating themselves.
arxiv  

Quality of life in schizophrenia: development, reliability and internal consistency of the Lancashire Quality of Life Profile – European Version [PDF]

open access: bronze, 2000
Luis Gaite   +9 more
openalex   +1 more source

Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding

open access: yesFEBS Open Bio, EarlyView.
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla   +4 more
wiley   +1 more source

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