Results 121 to 130 of about 1,761,271 (347)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Turkish version of the Tilburg Frailty Indicator
Clinical Interventions in Aging, 2019 Yildiray Topcu, Fatih Tufan, Cihan Kilic Department of Geriatrics, Istanbul School of Medicine, Istanbul University, Istanbul, Turkey Background: Recently frailty has drawn significant interest as an important predictor of several clinically relevant ...
Topcu Y, Tufan F, Kilic C
doaj
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Presentation of the first pilot version of the social competence and behavior evaluation scales - preschool edition (OLSP) and their construct validity [PDF]
Psihološka Obzorja, 2000 The contribution presents the first Slovenian version of the Social Competence and Behavior Evaluation - Preschool Edition (OLSP) scale. It was translated and adapted from the American original (SCBE) of the authors LaFreniere and Dumas (1995).
Maja Zupančič +2 more
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Internal Consistency and the Inner Model Hypothesis [PDF]
Bulletin of Symbolic Logic, 2006 There are two standard ways to establish consistency in set theory. One is to prove consistency using inner models, in the way that Gödel proved the consistency of GCH using the inner model L. The other is to prove consistency using outer models, in the way that Cohen proved the consistency of the negation of CH by enlarging L to a forcing extension L ...
openaire +4 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A primer on reliability testing of a rating scale
Indian Journal of PsychiatryIn this article, the second of a series on rating scale translation, adaptation, and psychometric testing, we focus on reliability testing of a rating scale.
Vikas Menon +5 more
doaj +1 more source