Results 71 to 80 of about 2,540,051 (294)

Benefits and case studies using internal curing of concrete

open access: yes, 2007
Proper curing of concrete is important to ensure that it achieves its intended performance and durability. Conventionally, this is achieved through external curing, applied after mixing, placing and finishing [1]. As demonstrated in the previous chapters
Cusson, D.
core  

Coupled visco-mechanical and diffusion void growth modelling during composite curing [PDF]

open access: yes, 2010
Most critical processing step during long fiber reinforced epoxy matrix composite laminate manufacturing is the polymerization stage. If not optimized, it gives birth to defects in the bulk material, such as voids.
Bernhart, Gérard   +10 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Enhance the properties of concrete using pre-developed burnt clay chips as internally curing concrete aggregate

open access: yesCase Studies in Construction Materials, 2019
Materials of internal curing concrete have been developed in many countries. Some of those materials are superabsorbent polymers, light weight aggregate (LWA), normal weight aggregate, recycled aggregate, bentonite clay, furnace slag and bottom ash.
M.M.H.W. Bandara   +2 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Chapter 9 - Benefits and case studies using internal curing of concrete

open access: yes, 2007
Proper curing of concrete is important to ensure that it achieves its intended performance and durability. Conventionally, this is achieved through external curing, applied after mixing, placing and finishing [1]. As demonstrated in the previous chapters
Cusson, D.
core  

Microscopic pore structure evolution and mechanical performance mechanism of CICA-modified high-performance concrete: optimization for crack resistance and freeze-thaw durability

open access: yesScientific Reports
High-performance concrete (HPC) is prone to early-age cracking due to its low water-to-binder ratio and high autogenous shrinkage, which compromises its durability and service life. Internal curing technology is regarded as a key approach to address this
Wei Li
doaj   +1 more source

The Investigation of Different Curing Regimes on Reactive Powder Concrete Strength: A Review

open access: yesJournal of Engineering
Enhancing the properties of reactive powder concrete (RPC) by developing the internal structure or making replacements or additions to the aggregates is becoming a prevalent method to obtain RPC with desired properties, which it can be used in numerous ...
Ahmed A. Luti, Zena K. Abbas
doaj   +1 more source

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