Results 51 to 60 of about 2,540,051 (294)

Unveiling the combined influence of higher molecular weight polyethylene glycol and superplasticizer chemistry on fresh, mechanical, and microstructural performance of internally cured mortar

open access: yesMaterials Research Express
The limitations of conventional water curing in tall structures and arid regions necessitate alternative hydration strategies. Use of internal curing agents in high strength concrete can effectively mitigate evaporation and promote enhanced cement ...
Kastro Kiran V, Dhanya Sathyan
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Investigation into Improved Pavement Curing Materials and Techniques: Part 2 - Phase III; TR-479, March 2003 [PDF]

open access: yes, 2003
Appropriate curing is important for concrete to obtain the designed properties. This research was conducted to evaluate the curing effects of different curing materials and methods on pavement properties.

core  

Effect of blended cements on effectiveness of internal curing in HPC

open access: yes, 2007
The effects of internal curing, type of blended cement and coarse aggregate size on early-age expansion, autogenous shrinkage and strength of high-performance concrete were investigated.
Cusson, D.
core   +1 more source

Water movement in Internally Cured Concrete

open access: yesIOP Conference Series: Materials Science and Engineering, 2018
Currently, ordinary cement concrete uses external curing. For high-strength or high-performance concrete, implementing external curing is difficult and inefficient. In these types of concrete, the rather large cement content and low water-binder ratio form very dense cement paste.
Hieu Duy Nguyen, Hung Quang Le
openaire   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Modelling and analysis of strength and durability properties of internal curing concrete using PEG 400 and artificial neural network

open access: yesDiscover Sustainability
The traditional curing processes necessitate a large amount of water. This is especially difficult in locations where there is a lack of water and for construction of high-rise structures.
Sowjanya Gowdra Virupakshappa   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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