Results 91 to 100 of about 3,979,336 (310)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Internal Evaluation of Residency Training Programs for Selected Specialized Groups at Guilan University of Medical Sciences: The Essential Need for Monitoring Specialized Training Courses [PDF]

open access: yesPizhūhish dar Āmūzish-i ̒ulūm-i Pizishkī
In the medical education environment, ensuring and continuously improving quality has become an indispensable necessity. This technical note examines the internal evaluation process of residency training programs at the school of medicine of Guilan ...
Jalal Kheirkhah   +5 more
doaj  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

INTERNAL AUDIT EFFICIENCY EVALUATION PRINCIPLES

open access: yesJournal of Business Economics and Management, 2007
Current business environment has experienced rapid and revolutionary change with far reaching consequences for companies worldwide. Management responses to fierce global competition include improved quality and risk management initiatives, reengineered structures and processes and greater accountability to ensure more timely, reliable and relevant ...
openaire   +5 more sources

Evaluation of Effective factor on the Education Performance of Medical physics group

open access: yesآموزش پزشکی, 2018
BACKGROUND AND OBJECTIVE: Improving the quality of education is done based on a method or model at each university. One of the methods and indicators for assessing educational quality is internal evaluation and each university will be able to plan and ...
Majid Jadidi   +3 more
doaj  

On Hilbert's Tenth Problem [PDF]

open access: yes, 2014
Using an iterated Horner schema for evaluation of diophantine polynomials, we define a partial $\mu$-recursive "decision" algorithm decis as a "race" for a first nullstelle versus a first (internal) proof of non-nullity for such a polynomial -- within a ...
Pfender, Michael
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Evaluating an intern/residency program

open access: yesJournal of Osteopathic Medicine, 1992
Abstract When faced with the task of program evaluation, many directors of medical education may find themselves overwhelmed. This article presents suggestions for conducting an evaluation, including the six basic elements to consider before embarking on such an undertaking.
openaire   +2 more sources

Selection and use of TLDS for high precision NERVA shielding measurements [PDF]

open access: yes, 1972
An experimental evaluation of thermoluminescent dosimeters was performed in order to select high precision dosimeters for a study whose purpose is to measure gamma streaming through the coolant passages of a simulated flight type internal NERVA reactor ...
Woodsum, H. C.
core   +1 more source

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