Results 41 to 50 of about 2,256,279 (307)

Internal exposure levels of thyroid 131I in nuclear medical staff

open access: yes环境与职业医学, 2023
BackgroundBased on numerous epidemiological studies, radionuclide 131I can result in thyroid disease. ObjectiveTo study the contamination level of thyroid 131I in 131I treatment associated radiation workers in nuclear medicine departments in Shanghai ...
Bin WANG   +5 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Toxic effects of PFOS/PFOA and their internal exposure in Chinese general population

open access: yesZhongguo shipin weisheng zazhi, 2022
As widely used synthetic chemicals, perfluorooctane sulfonic acid (PFOS) and perfluorooctanic acid (PFOA) are ubiquitous in the environment and the human body.
HAO Lili   +3 more
doaj   +1 more source

Special treatment reduces helium permeation of glass in vacuum systems [PDF]

open access: yes, 1966
Internal surfaces of the glass component of a vacuum system are exposed to cesium in gaseous form to reduce helium permeation. The cesium gas is derived from decomposition of cesium nitrate through heating.
Bryant, P. J., Gosselin, C. M.
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Mussel eggs as indicators of mutagen exposure in coastal and estuarine environments [PDF]

open access: yes, 1994
The aim of this study was to develop a short-term genotoxicity assay for monitoring the marine environment for mutagens. Based on the developing eggs and embryos of the marine mussel Mytilus edulis, an important pollution indicator species, the test ...
Dixon, D.R., Pascoe, P.L
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The African Lungfish (\u3cem\u3eProtopterus dolloi\u3c/em\u3e): Ionoregulation and Osmoregulation in a Fish out of Water [PDF]

open access: yes, 2007
Although urea production and metabolism in lungish have been thoroughly studied, we have little knowledge of how internal osmotic and electrolyte balance are controlled during estivation or in water.
Galvez, Fernando   +6 more
core   +1 more source

Astrometric calibration and performance of the Dark Energy Camera [PDF]

open access: yes, 2017
We characterize the ability of the Dark Energy Camera (DECam) to perform relative astrometry across its 500~Mpix, 3 deg^2 science field of view, and across 4 years of operation.
A. A. Plazas   +56 more
core   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

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