Results 61 to 70 of about 2,277,571 (305)

Reduction of Outdoor and Indoor PM2.5 Source Contributions via Portable Air Filtration Systems in a Senior Residential Facility in Detroit, Michigan

open access: yesToxics, 2023
Background: The Reducing Air Pollution in Detroit Intervention Study (RAPIDS) was designed to evaluate cardiovascular health benefits and personal fine particulate matter (particulate matter < 2.5 μm in diameter, PM2.5) exposure reductions via portable ...
Zachary M. Klaver   +6 more
doaj   +1 more source

Financial Exchange Rates and International Currency Exposures [PDF]

open access: yesAmerican Economic Review, 2007
In order to gain a better empirical understanding of the international financial implications of currency movements, we construct a database of international currency exposures for a large panel of countries over 1990-2004. We show that trade-weighted exchange rate indices are insufficient to understand the financial impact of currency movements and ...
Philip Lane, Jay C. Shambaugh
openaire   +7 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Progress on internal exposure to typical environmental persistent organic pollutants and cancer

open access: yes环境与职业医学
Environmental pollution is closely linked to the occurrence and development of cancer. Chemical carcinogens are the most important environmental factors causing cancer in humans. Among them, persistent organic pollutants (POPs) are characterized by their
Xuerui MA   +5 more
doaj   +1 more source

Tririum in urine in residents of Ozyorsk, the Chelyabinsk region in 2016

open access: yesРадиационная гигиена, 2019
Objectives. To create the model of relation between volume activity of tritium in urine of Ozyorsk residents and physical and biological factors. To define the correspondence of internal exposure doses of Ozyorsk residents obtained from tritium to ...
L. V. Finashov   +2 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Peroxidase activity of the rat blood at prolonged intake of 137Cs [PDF]

open access: yesЯдерна фізика та енергетика, 2013
Investigated peroxidase activity of blood white nonlinear rats-males by daily oral administration of 15 kBq 137Cs by chemiluminescence. Discovered oscillatory nature of the changes chemiluminescent indicators peroxi-dase oxidation of blood, the maximum ...
Yu. P. Grynevych   +4 more
doaj  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

NATURAL IONIZING IRRADIATION SOURCES IN TYVA REPUBLIC

open access: yesРадиационная гигиена, 2015
Average annual individual effective doses from natural exposure of the population of Russian Federation are very diverse. At the same time exposure doses inside one territory could also be very different from the average value for this territory. In this
S. A. Daktaalai
doaj  

Association between the urine tobacco metabolite levels and physical health in Chinese primary school students with secondhand smoke exposure

open access: yesFrontiers in Public Health
BackgroundThere is limited epidemiological evidence on the association between secondhand smoke exposure and growth and developmental problems in children and adolescents.
Menghan Cheng   +8 more
doaj   +1 more source

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