Results 61 to 70 of about 36,891 (314)
Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Numerical simulation of buckling behavior of the buried steel pipeline under reverse fault displacement [PDF]
Mechanical Sciences, 2015 Reverse fault movement is one of the threats for the structural integrity of buried oil-gas pipelines caused by earthquakes. Buckling behavior of the buried pipeline was investigated by finite element method.
J. Zhang, Z. Liang, C. J. Han, H. Zhang
doaj +1 more source
A generalized fault isolability matrix for improved fault diagnosability analysis
, 2016 A generalized fault isolability matrix is proposed for quantitative analysis of fault isolability properties. The original fault isolability matrix gives information about which faults that are isolable from each other.
Jung, Daniel,, Daniel Jung
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Robust fault detection for networked systems with distributed sensors
, 2011 Copyright [2011] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Zidong Wang +7 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Characterisation of the 2D and 3D density and connectivity attributes of fracture systems in carbonate reservoir analogues: implications for fluid flow [PDF]
, 2013 Fault zones, hosted in fractured carbonate reservoirs, can behave as either high porosity and permeability conduits, favoring the migration of fluids; or, conversely, as low porosity and permeability barriers, retarding fluid flow, due to the presence of
Sagi, David Adam, SAGI, DAVID,ADAM
core
Research on Wind Turbine Fault Detection Based on the Fusion of ASL-CatBoost and TtRSA
, 2023 The internal structure of wind turbines is intricate and precise, although the challenging working conditions often give rise to various operational faults.
Lingchao Kong +3 more
core +1 more source