Results 71 to 80 of about 36,891 (314)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Renewable energy line protection based on voltage traveling wave polarity
电力工程技术Renewable energy has weak feedforward and controlled characteristics, so the traditional industrial frequency protection does not work when renewable energy is sent out through AC transmission line.
YE Yuanbo +5 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Internal fault additional network.
, 2019 Internal fault additional network.
Xingxing Dong (6495335) +2 more
core +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Detection and Diagnosis of Motor Stator Faults using Electric Signals from Variable Speed Drives [PDF]
, 2015 Motor current signature analysis has been investigated widely for diagnosing faults of induction motors. However, most of these studies are based on open loop drives.
Shaeboub, Abdulkarim +9 more
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Analysis and Protection Scheme of Station Internal AC Grounding Faults in a Bipolar MMC-HVDC System
IEEE Access, 2020 The symmetrical bipolar configuration shows a great advantage in modular multilevel converter (MMC) based high-voltage dc-current (HVDC) transmission. In a bipolar MMC-HVDC system, station internal ac grounding faults cause sub-module (SM) capacitors to ...
Shimin Xue +3 more
doaj +1 more source
Fault rock evolution and fluid flow in sedimentary basins [PDF]
, 1989 Structural studies have been undertaken in two extensional fault regimes associated with post-Caledonian basin-forming events in northern Scotland. A combination of detailed mapping and microstructural analysis has revealed the deformation processes and ...
Hippler, Susan Johanna
core