Results 51 to 60 of about 484,641 (333)

Internal Fixation of Femoral Neck Fractures [PDF]

, 2015
__Abstract__ This thesis consists of three parts. Part 1 described aspects of the organization of trauma related trials. Part 2 analyzed the uniformity of current femoral neck fracture treatment and adherence to the Dutch guideline on hip fracture ...
Zielinski, S.M. (Stephanie)
core  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Finite element analysis of retrograde superior ramus screw of pubis for the treament of pelvic anterior ring fracture

Journal of Orthopaedic Surgery and Research
Background Retrograde superior ramus screw of pubis (SRSP) is a new kind of pelvic minimally invasive internal fixation apparatus developed by our team.
Gu Meiqi, Xu Zhe, Li Yifei, Xiang Penghui, Wang Zhen, Zhang Rui, Xin Fei, Tang Zhaohui, Yi Chengla   +8 more
doaj   +1 more source

Review article: Risk factors of infection following total knee arthroplasty [PDF]

, 2012
22 PubMed articles in English were identified using the key words: ‘risk factors’, ‘infection’, and ‘primary total knee arthroplasty (TKA)’. The 10 most relevant articles were reviewed. In one study, obesity and diabetes were considered risk factors
Rodríguez Merchán, E. Carlos
core   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Combined Internal and External Fixation for Charcot Neuro Arthropathy: 1 Year Results

Foot & Ankle Orthopaedics, 2022
Category: Diabetes Introduction/Purpose: Complex foot and ankle deformities secondary to charcot neuroarthropathy continue to represent a significant challenge and management quandary.
Muhammed H. Iqbal MD, Sultan N. Qasim FRCS(Tr&Orth), Simon Chambers FRCS   +2 more
doaj   +1 more source

Complications of Rigid Internal Fixation [PDF]

Craniomaxillofacial Trauma & Reconstruction, 2009
Over the past 20 years, there have been many advances in the development of bone fixation systems used in the practice of craniomaxillofacial surgery. As surgical practices have evolved, the complications of each technologic advance have changed accordingly. Interfragmentary instability of interosseous wiring has been replaced by the risk of exposure,
Chris A Campbell, Kant Y. Lin
openaire   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Complications Associated with Volar Locking Plate Fixation of Distal Radial Fractures. [PDF]

, 2018
Volar locked plating is the most frequently utilized method for internal fixation of distal radial fractures. The overall complication rate for volar plating of distal radial fractures appears to be relatively low compared with other operative fixation ...
Alter, Todd H., Ilyas, Asif M.
core   +1 more source