Results 71 to 80 of about 3,254,373 (396)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Assesment [sic] of cement augmentation and screw trajectory on pedicle screw fixation in osteoporotic vertebrae [PDF]
, 2010 Internal fixation of osteoporotic spines for fracture or deformity is currently difficult, owing to failure at the bone- implant interface. This study aims to ascertain whether pedicle screw trajectory and pedicle cortex retention can independently ...
Hirner, Jesse +1 more
core
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Journal of Orthopaedic Surgery and ResearchBackground Retrograde superior ramus screw of pubis (SRSP) is a new kind of pelvic minimally invasive internal fixation apparatus developed by our team.
Gu Meiqi +8 more
doaj +1 more source
BMC Musculoskeletal Disorders, 2023 Background Self-lock compression anti-rotation blade (SCAB) is a novel internal fixation implant for femoral neck fractures (FNF). We conducted this finite element analysis study to evaluate the biomechanical performances of SCAB combined with a ...
Bo-Xuan Huang +3 more
doaj +1 more source
Complications of Rigid Internal Fixation [PDF]
Craniomaxillofacial Trauma & Reconstruction, 2009 Over the past 20 years, there have been many advances in the development of bone fixation systems used in the practice of craniomaxillofacial surgery. As surgical practices have evolved, the complications of each technologic advance have changed accordingly. Interfragmentary instability of interosseous wiring has been replaced by the risk of exposure,
Chris A Campbell, Kant Y. Lin
openaire +3 more sources
THE EFFECT OF DZIKIR CONCERNING TO PAIN LEVEL AFTER SURGICAL OPERATION REDUCTION INTERNAL FIXATION (ORIF) [PDF]
, 2015 Background: Surgical operation of ORIF affect painful which disturb the patient’s comfortable. Dzikir have psychological benefit psichologis which affect comfortable and spiritual feelings focused to Allah, so could give a relaxation effect to percepts ...
Misnawati, Wiwik +1 more
core
Action, arousal and subjective time [PDF]
, 2004 Saccadic chronostasis refers to the subjective temporal lengthening of the first visual stimulus perceived after an eye movement. It has been quantified using a duration discrimination task.
Allan +43 more
core +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Journal of International Medical Research, 2022 Objective This study was performed to investigate the risk factors related to surgical site infection (SSI) secondary to spinal internal fixation via the posterior approach.
XiangHui Dong, Yongchun Zhou
doaj +1 more source