Results 51 to 60 of about 824,640 (257)

Deformation of face-centered cubic polycrystal and stress tensor components in grains [PDF]

, 2016
The transmission electron microscopy (TEM) has been used to indicate the contribution of stress tensorcomponents to internal stresses in deformed polycrystalline austenitic steel.
Gibert, Ivan, Kiseleva, Svetlana, Koneva, Nina, Popova, Natalya   +3 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Gradient material Pd-PdHx

Литьë и металлургия, 2018
There was analyzed videotape recording of palladium plate bending during its one-side saturation with hydrogen in experimental conditions of isothermal temperature 130 °С, step hydrogening up to РН2 = 0,01 МPа, 0,033, 0,05 МPа.
M. V. Goltsova, I. G. Zhirov, D. A. Nazarov   +2 more
doaj   +1 more source

On the Use of Constitutive Internal Variable Equations for Thermal Stress Predictions in Aluminium Casting [PDF]

Modeling, Identification and Control, 1993
The report discusses the use of constitutive equations with internal variables in mathematical calculations of the thermally induced strains and stresses that arise during casting of aluminium.
Asbjørn Mo, Erik J. Holm
doaj   +1 more source

Effective refractive index tensor for weak field gravity

, 2004
Gravitational lensing in a weak but otherwise arbitrary gravitational field can be described in terms of a 3 x 3 tensor, the "effective refractive index".
Celine Cattoen, Matt Visser, Misner C W, Mollerach S, Novello M, Penrose R Sorkin R D Woolgar E, Petarpa Boonserm, Schneider P, Schutz B F, Sereno M, Silke Weinfurtner, Tristan Faber, Visser M, Visser M, Visser M Bassett B Liberati S Burgess C P Meyers R C   +14 more
core   +3 more sources

Numerical derivation of constitutive models for unbonded flexible risers [PDF]

, 2009
This is the post-print version of the final paper published in International Journal of Mechanical Sciences. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections,
Alfano, G, Bahai, H, Bahtui, A
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The effectiveness of the effect of microwave radiation and convection heating on the relaxation of internal stresses in cured polymer composite materials [PDF]

Известия Саратовского университета. Новая серия: Физика
Background and Objectives: The relaxation of internal stresses in pressed carbon and fiberglass plastics under the action of bending loads after modification by heating in a thermal chamber and exposure to a microwave electromagnetic field has been ...
Zlobina, Irina V., Bekrenev, Nikolaj Valeryevich, Churikov, Danila Olegovich   +2 more
doaj   +1 more source

Analysis of AC link topologies in non-isolated DC/DC triple active bridge converter for current stress minimization [PDF]

, 2017
This paper presents analysis of the non-isolated DC/DC triple active bridge (TAB) converter under various purely inductor-based AC link topologies. The objective of the analysis is to find the topology that incorporates the least value of the AC link ...
Aboushady, Ahmed A., Ahmed, Khaled H., Hebala, Osama M.   +2 more
core   +3 more sources