Results 101 to 110 of about 5,045,034 (354)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The regulation of ferrocene-based catalysts on heat transfer in high-pressure combustion of ammonium perchlorate/hydroxyl-terminated polybutadiene/aluminum composite propellants

Defence Technology
The regulation of the burning rate pressure exponent for the ammonium perchlorate/hydroxyl-terminated polybutadiene/aluminum (AP/HTPB/Al) composite propellants under high pressures is a crucial step for its application in high-pressure solid rocket ...
Jinchao Han, Songqi Hu, Linlin Liu
doaj   +1 more source

Analytical solutions for the internal forces of lining structure in shallow double-arched tunnel subject to unsymmetrical loads [PDF]

, 2020
Xiaochang Li, Song Yang, Rui Dai, Zubin Ai, Chao Zhang, Xin Huang   +5 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Study on the nonlinear viscoelastic behavior of rubber composites filled with silica

Alexandria Engineering Journal
Silica-filled rubber composites exhibit nonlinear viscoelastic behavior depending on filler dispersion and matrix interaction. This study investigated the effects of silane treatment on dynamic mechanical properties of precipitated and fumed silica ...
Pan Wang, Peijin Liu, Wen Ao
doaj   +1 more source

Revealing the Structure and Internal Rotation of the Sagittarius Dwarf Spheroidal Galaxy with Gaia and Machine Learning [PDF]

, 2021
Andrés del Pino, Mark A. Fardal, Roeland P. van der Marel, Ewa L. Łokas, Cecilia Mateu, Sangmo Tony Sohn   +5 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Effect of toolpath in large-format additive manufacturing with bio-derived composites

Virtual and Physical Prototyping
There has been growing interest in integrating bio-derived composites into Large-format additive manufacturing (LFAM) feedstocks to reduce the use of petroleum-derived materials and reduce the overall carbon footprint of LFAM.
Eonyeon Jo, Katie Copenhaver, Halil Tekinalp, Tyler Smith, Hsin Wang, Uday Vaidya, Soydan Ozcan, Seokpum Kim   +7 more
doaj   +1 more source

Measuring the Master Adaptive Learner: Development and Internal Structure Validity Evidence for a New Instrument [PDF]

, 2022
J.K. Stringer, Larry D. Gruppen, Michael S. Ryan, Samara Ginzburg, William B. Cutrer, Margaret Wolff, Sally A. Santen   +6 more
openalex   +1 more source