Results 141 to 150 of about 8,905 (245)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Extended minds and prime mental conditions: probing the parallels [PDF]

open access: yes, 2018
Two very different forms of externalism about mental states appear prima facie unrelated: Williamson’s (1995, 2000) claim that knowledge is a mental state, and Clark & Chalmers’ (1998) extended mind hypothesis.
Drayson, Zoe
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Multiscale integration: beyond internalism and externalism. [PDF]

open access: yesSynthese, 2021
Ramstead MJD   +3 more
europepmc   +1 more source

Appropriate Belief Without Evidence [PDF]

open access: yes, 2015
In this paper I defend a version of Wittgensteininan contextualism. This is a view about justification on which some beliefs are epistemically appropriate because evidence cannot be adduced in their favour.
Ashton, Natalie Alana
core  

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Review of Teed Rockwell’s Neither Brain nor Ghost: A Nondualist Alternative to the Mind-Brain Identity Theory [PDF]

open access: yes, 2006
Review of Teed Rockwell’s Neither Brain nor Ghost: A Nondualist Alternative to the Mind-Brain Identity ...
Marsh, Leslie
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

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