This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
‘Putting apes (body and language) together again’, a review article of Savage-Rumbaugh, S., Taylor, T. J., and Shanker, S. G. Apes, Language, and the Human Mind (Oxford: 1999) and Clark, A. Being There: Putting Brain, Body, and World Together Again (MIT: 1997) [PDF]
It is argued that the account of Savage-Rumbaugh’s ape language research in Savage-Rumbaugh, Shanker and Taylor (1998. Apes, Language and the Human Mind.
Cowley, Stephen, Spurrett, David
core
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
Allameh Tabataba'i and Finiss on Moral Motivations: A Comparative Study [PDF]
In the psychology of ethics, there is a question concerning the true nature of moral motivations; are they internal or external motivations, are they self-controlled or not?
rahim dehghan
doaj
How Far we Can Go Without Looking Under the Skin: The Bounds of Cognitive Science
The aim of this paper is to discuss the concept of distributed cognition (DCog) in the context of classic questions posed by mainstream cognitive science.
Afeltowicz Łukasz, Wachowski Witold
doaj +1 more source
Evidence, Epistemic Luck, Reliability, and Knowledge. [PDF]
Engel M.
europepmc +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Should Assessments of Decision-Making Capacity Be Risk-Sensitive? A Systematic Review. [PDF]
Berens NC, Kim SYH.
europepmc +1 more source

