Results 41 to 50 of about 421 (226)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

RATIONALITY: NORMAL MENTAL FUNCTIONING OR PSYCHOLOGICAL COHERENCE?

open access: yesProblemos, 2012
A version of the rationalist internalist argument, employing a pro tanto reading of the term “normative reason”, is often criticized due to its conception of rationality.
Ieva Vasilionytė
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

An Indian Debate on Semantic Internalism and Externalism: Śāntarakṣita’s Tattvasaṃgraha on the Meaning of Words

open access: yesReligions
The semantic internalist–externalist debate is one of the central themes in contemporary philosophy. The present paper aims to explore the dispute between Śāntarakṣita and his opponents over the meaning of words (śabdārtha) in the śabdārthaparīkṣā ...
Long Yin Sin
doaj   +1 more source

Du quotidien au droit ou la compréhension du droit par l’étude du quotidien des juristes

open access: yesCahiers Jean Moulin, 2019
Everyday life is an unusual matter for the legal research; indeed, it is wrongly often relegated to the fields of sociology or political science. Yet, the study of the everyday law can nevertheless reveal valuable lessons for the jurist, provided of ...
Michael Koskas
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Luka eksplanacyjna a pojęcia własności fenomenalnych stanowisko Josepha Levine’a ( Explanatory gap and the concept of phenomenal properties: Joseph Levine’s view) [PDF]

open access: yesAnaliza i Egzystencja, 2012
The explanatory gap problem arises in the context of the mind-body relation, and especially the phenomenal concepts-physical concepts relation. It is posed as a question about the method which is appropriate for the reduction of consciousness to physical
Adriana Schetz
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

On the significance of L. Zagzebski’s results for solving the Gettier problem

open access: yesИнтеллект. Инновации. Инвестиции
The article is devoted to the analysis of the authoritative research results of L. Zagzebski on the Gettier problem, which has not been solved for many years.
R. A. Yartsev
doaj   +1 more source

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