Results 141 to 150 of about 4,355,632 (331)
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang+16 more
wiley +1 more source
Cooper pair tunneling in circuits with substantial dissipation: the three-junction R-pump for single Cooper pairs [PDF]
We propose a circuit comprising a linear array of three small-capacitance superconducting tunnel junctions with miniature resistors (R > R_Q = h/4e^2 = 6.5 kOhm) attached to the ends of this array. Owing to the Coulomb blockade effect and the effect of dissipative environment on the supercurrent, this circuit enables the gate-controlled transfer of ...
arxiv
Machine Learning‐Enabled Drug‐Induced Toxicity Prediction
Unexpected toxicity accounts for 30% of drug development failures. This review highlights ML innovations in predicting drug‐induced toxicity, emphasizing comparative analyses, interpretable algorithms, and multi‐source data integration. It categorizes toxicity types, summarizes ML models, and organizes key databases, offering strategies to address ...
Changsen Bai+5 more
wiley +1 more source
International cooperation to fight cancer's late-stage presentation in low- and middle-income countries. [PDF]
Henke O+11 more
europepmc +1 more source
Saving the Past for the Future-Tales of International Search and Cooperation [PDF]
Ted Powell
openalex +1 more source
Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration
The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan+16 more
wiley +1 more source
International cooperation through big science programs. [PDF]
Poo MM.
europepmc +1 more source