Results 161 to 170 of about 1,870,973 (291)

Getting ready for the millennium round trade negotiations: [PDF]

open access: yes
Contents: 1. Overview / Eugenio Diaz-Bonilla and Sherman Robinson 2. Latin American perspective / Eugenio Diaz-Bonilla and Lucio Reca 3. Asian perspective / Marcus Noland 4. African perspective / Natasha Mukherjee and Rebecca Lee Harris 5.
Diaz-Bonilla, Eugenio, ed.   +1 more
core  

Post‐Translational Modifications of TOE3 Regulate Antiviral Defense in Tobacco

open access: yesAdvanced Science, EarlyView.
CK2αL phosphorylates TOE3 and enhances its stability, while FBXL1 promotes the ubiquitination‐degradation of TOE3 via the 26S proteasome. Compared to CK2αL‐phosphorylated TOE3, nonphosphorylated TOE3 shows a much higher affinity for FBXL1 and is more susceptible to ubiquitination‐degradation, thus facilitating viral infection. The regulatory mechanisms
Bolei Jiao   +3 more
wiley   +1 more source

EU-NICE, Eurasian University Network for International Cooperation in Earthquakes [PDF]

open access: yes, 2012
Despite the remarkable scientific advancements of earthquake engineering and seismology in many countries, seismic risk is still growing at a high rate in the world’s most vulnerable communities.
Braga, F.   +20 more
core   +1 more source

Engineered Fusion Enzyme‐Mediated Non‐Consecutive Cyclization‐Glycosylation Enables Heterologous Synthesis of Antifungal Enfumafungin

open access: yesAdvanced Science, EarlyView.
The artificial biosynthetic pathway potentially involved in biosynthesis of enfumafungin is first reconstructed in an optimized Aspergillus oryzae chassis with the increased site‐specific integration efficiency and shortened time for marker recycling, which requires an artificial fusion enzyme EfuA(TC)FsoA(GT).
Yaohui Gao   +11 more
wiley   +1 more source

Effective e-waste management-The role of international cooperation and fragementation [PDF]

open access: yes
E-waste problems related to trade in wastes and informal recycling in the developing countries address environmental, social, and economic effects. Moreover, given on multiple aspect considerations, it is found that currently recycling fragmentation ...
Chen, Yenming, Wu, Tien-Hua
core   +1 more source

Novel Evolutionarily Conserved Oncogene COA4 is Driven by KRAS Mutant and Promotes Cancer Metastasis Through Dual Mitochondrial Metabolism‐Dependent and ‐Independent Mechanisms

open access: yesAdvanced Science, EarlyView.
In KRAS‐mutant tumors, KRAS transcriptionally upregulates COA4 via the PI3K/AKT/E2F1 axis, promoting metastasis. Mechanistically, COA4 enhances tumor cell migration through dual pathways: within mitochondria, it boosts oxidative phosphorylation; in the cytoplasm, it binds and activates CDC42 to stimulate pseudopodia formation.
Xingzhao Ji   +14 more
wiley   +1 more source

The importance of Intermediaries organizations in international R&D cooperation: an empirical multivariate study across Europe [PDF]

open access: yes
Despite the large number of publications related to business cooperation in R&D and the wide perception of the importance of intermediary institutions in the R&D cooperation process, empirical studies on its role are scarce, scattered and fragmented ...
Aurora A.C. Teixeira, Margarida Catarino
core  

BHLHE40 Cooperates with GATA2/3 to Control Human Syncytiotrophoblast Lineage Differentiation

open access: yesAdvanced Science, EarlyView.
BHLHE40 interacts directly with GATA2 and GATA3 and co‐occupies genomic loci critical for STB differentiation and function. BHLHE40 also affects GATA2/3 binding at enhancer and promoter regions. Moreover, BHLHE40 is potentially involved in genome‐wide remodeling of H3K4me3 and H3K27ac chromatin landscapes through GATA2/3 recruitment, activating ...
Lijin Peng   +11 more
wiley   +1 more source

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