Results 31 to 40 of about 168,556 (311)
Discover GeoscienceSulfate scattering is an indicator of diverse aspects of atmospheric interactions and climate change dynamics. In this study, we attempted to use Machine Learning frameworks to sieve the vital factors that can be used in studying sulfate scattering using
Jagadish Kumar Mogaraju
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NECESSITY OF A NEW TYPE OF SYMBIOSIS BETWEEN THE NOMINAL AND THE REAL ECONOMY [PDF]
Financial Studies, 2013 This paper deals with the rift between the nominal economy and the evolution of the real economy, which represented the main structural cause for the international crisis (since 2007/2008), followed by a prolonged recession and a stagnant growth rate ...
Lucian C. IONESCU
doaj
Communications, 2018 Evacuation is one of the main tasks of administration and its forces and resources in different types of extraordinary events, as well as natural and anthropogenic (non-military and military events) unusual/emergency situations.
Marcin Paweska, Jozef Ristvej
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RUDN Journal of Economics, 2021 The economic crisis in the United States and its spread to continental Europe caused a financial crisis in European stock markets, which in turn reduced production in Europe, resulting in rising unemployment, that eventually led to protests against the ...
Aref Bijan, Ehsan Ejazi
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The Polish-Lithuanian Crisis of March 1938. Some Romanian and Western reactions [PDF]
Revista Română pentru Studii Baltice şi Nordice, 2010 In March 1938, when the eyes of the entire Europe were trained on the events in Austria that culminated with the Anschluss, there was another conflict on the European continent that bothered the Western powers, and not only.
Bogdan Schipor
doaj
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source