Results 41 to 50 of about 8,662 (165)

ULUSLARARASI KRİZLERDE KRİZ İLETİŞİMİ VE UYGULAMASI

open access: yesSosyal Ekonomik Araştırmalar Dergisi, 2005
Günümüzde kriz kavramı, globalleşme olgusunun etkisiyle birlikte; gerek yerel gerekse küresel çevrelerde sosyal hayatın baskın ve kanıksanan kavramlarından biri olarak karşımıza çıkmaktadır. Bu nedenle, II.
Emrah Aydemir
doaj   +2 more sources

The international currency crisis

open access: yesSouth African Journal of Business Management, 1971
No abstract available.
F. J.C. Cronje
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Effects of National Identity in Transnational Crises: Implications of Social Identity Theory for Attribution and Crisis Communications

open access: yesInternational Journal of Communication, 2016
This study addresses the current gap in international crisis communications literature by introducing principles of social identity theory into the existing body of crisis communications theory.
Jonathan Borden
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The problem of legitimacy of political power in modern Russia

open access: yesКонтуры глобальных трансформаций: политика, экономика, право, 2016
The article deals with the general theoretical analysis of such a category as “legitimacy” and the mechanisms of legitimization of political power. The authors research the nature of crises of legitimacy and the approaches for getting over them.
Alexander Vershinin, Nikita Molchakov
doaj  

BOOK REVIEW: NEETA INAMDAR, PRIYA VIJAYKUMAR POOJARY, AND PRAVEEN SHETTY, CONTOURS OF INDIA-EU ENGAGEMENTS: MULTIPLICITY OF EXPERIENCES, MANIPAL: MANIPAL UNIVERSAL PRESS, 2021, 451 PP.

open access: yesStudia Universitatis Babeş-Bolyai. Studia Europaea, 2023
India is becoming a major player on the international stage, with a very ambitious political agenda and ambitious plans for changing the course of world affairs.
George Horațiu BONTEA
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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