Results 51 to 60 of about 16,482,328 (245)
ULUSLARARASI KRİZLERDE KRİZ İLETİŞİMİ VE UYGULAMASI
Günümüzde kriz kavramı, globalleşme olgusunun etkisiyle birlikte; gerek yerel gerekse küresel çevrelerde sosyal hayatın baskın ve kanıksanan kavramlarından biri olarak karşımıza çıkmaktadır. Bu nedenle, II.
Emrah Aydemir
doaj +2 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
NECESSITY OF A NEW TYPE OF SYMBIOSIS BETWEEN THE NOMINAL AND THE REAL ECONOMY [PDF]
This paper deals with the rift between the nominal economy and the evolution of the real economy, which represented the main structural cause for the international crisis (since 2007/2008), followed by a prolonged recession and a stagnant growth rate ...
Lucian C. IONESCU
doaj
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The Polish-Lithuanian Crisis of March 1938. Some Romanian and Western reactions [PDF]
In March 1938, when the eyes of the entire Europe were trained on the events in Austria that culminated with the Anschluss, there was another conflict on the European continent that bothered the Western powers, and not only.
Bogdan Schipor
doaj
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
This study addresses the current gap in international crisis communications literature by introducing principles of social identity theory into the existing body of crisis communications theory.
Jonathan Borden
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source

