Results 51 to 60 of about 16,482,328 (245)

ULUSLARARASI KRİZLERDE KRİZ İLETİŞİMİ VE UYGULAMASI

open access: yesSosyal Ekonomik Araştırmalar Dergisi, 2005
Günümüzde kriz kavramı, globalleşme olgusunun etkisiyle birlikte; gerek yerel gerekse küresel çevrelerde sosyal hayatın baskın ve kanıksanan kavramlarından biri olarak karşımıza çıkmaktadır. Bu nedenle, II.
Emrah Aydemir
doaj   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

NECESSITY OF A NEW TYPE OF SYMBIOSIS BETWEEN THE NOMINAL AND THE REAL ECONOMY [PDF]

open access: yesFinancial Studies, 2013
This paper deals with the rift between the nominal economy and the evolution of the real economy, which represented the main structural cause for the international crisis (since 2007/2008), followed by a prolonged recession and a stagnant growth rate ...
Lucian C. IONESCU
doaj  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The Polish-Lithuanian Crisis of March 1938. Some Romanian and Western reactions [PDF]

open access: yesRevista Română pentru Studii Baltice şi Nordice, 2010
In March 1938, when the eyes of the entire Europe were trained on the events in Austria that culminated with the Anschluss, there was another conflict on the European continent that bothered the Western powers, and not only.
Bogdan Schipor
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Effects of National Identity in Transnational Crises: Implications of Social Identity Theory for Attribution and Crisis Communications

open access: yesInternational Journal of Communication, 2016
This study addresses the current gap in international crisis communications literature by introducing principles of social identity theory into the existing body of crisis communications theory.
Jonathan Borden
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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