Results 61 to 70 of about 2,192,184 (309)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
ULUSLARARASI KRİZLERDE KRİZ İLETİŞİMİ VE UYGULAMASI
Sosyal Ekonomik Araştırmalar Dergisi, 2005 Günümüzde kriz kavramı, globalleşme olgusunun etkisiyle birlikte; gerek yerel gerekse küresel çevrelerde sosyal hayatın baskın ve kanıksanan kavramlarından biri olarak karşımıza çıkmaktadır. Bu nedenle, II.
Emrah Aydemir
doaj +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Institutions, Information, and Trade Policy in Times of Crisis [PDF]
, 2011 The paper examines the role of international institutions in preventing the rise of protectionism in times of times of crisis. Economic crisis exacerbates uncertainty in the conduct of commercial relations and thus makes it more likely for countries to ...
Baccini, Leonardo, Kim, Soo Yeon
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Young people's mental and social distress in times of international crisis: evidence from helpline calls, 2019-2022. [PDF]
Sci Rep, 2023 Brülhart M, Klotzbücher V, Lalive R.
europepmc +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
A Component-Based Approach to Early Warning Systems: A Theoretical Model
Applied SciencesNatural hazards pose an increasing threat to society, necessitating the development of effective early warning systems (EWSs). This paper explores their critical role in mitigating the impacts of natural hazards.
Daniel Chovanec +5 more
doaj +1 more source
Police Building in Timor-Leste – Mission Impossible? [PDF]
, 2015 政治学 / Political Science and International RelationsIn the quest to find a success story of international police building, eyes often turn towards Timor-Leste.
DELLA-GIACOMA Jim +1 more
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source