Results 101 to 110 of about 56,745 (303)

Financial Liberalisation and Political Variables: a response to Abiad and Mody [PDF]

We challenge recent findings by Abiad and Mody (2005) which suggest that financial liberalization has little to do with political variables. This analysis is at odds with some of the established literature, and only with difficulty comes to terms with ...
Brian Burgoon, Geoffrey Underhill, Panicos Demetriades   +2 more
core   +3 more sources

Can IOs influence attitudes about regulating "Big Tech"? [PDF]

Rev Int Organ, 2023
Chapman TL, Li H.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

André Morizet, un intellectuel critique en Russie soviétique

Cahiers d’histoire
André Morizet, born of revolutionary unionism, magazine man, doctor of law, mayor of Boulogne-sur-Seine in 1919, joined the French Communist Party from its foundation.
Pascal Guillot
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Causes and consequences of language manipulation with the concept of «patriotism» and criteria its distinction with nationalism

Неофилология
INTRODUCTION. The concepts of “nationalism” and “patriotism”, “nazification” and “denazification” are used in the modern context without taking into account the history of their formation, which increases the possible escalation of social conflicts.
V. I. Mozgovoy
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

‘The persistence of national identity in the international art market’. Review of: Art Crossing Borders: The Internationalisation of the Art Market in the Age of Nation States, 1750-1914, edited by Jan Dirk Baetens and Dries Lyna, Amsterdam: Brill, 2019 [PDF]

Journal of Art Historiography, 2019
With their edited volume of essays dedicated to case studies of the art market during the long nineteenth century, Jan Dirk Baetens and Dries Lyna bring together research into specific cases that provide examples of the increasing internationalization of
Elizabeth A. Pergam
doaj