Results 51 to 60 of about 7,288,337 (357)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Rapid rise and decay in petition signing

open access: yesEPJ Data Science, 2017
Contemporary collective action, much of which involves social media and other Internet-based platforms, leaves a digital imprint which may be harvested to better understand the dynamics of mobilization. Petition signing is an example of collective action
Taha Yasseri   +2 more
doaj   +1 more source

On the Geographic Location of Internet Resources [PDF]

open access: yes, 2002
One relatively unexplored question about the Internet's physical structure concerns the geographical location of its components: routers, links and autonomous systems (ASes).
Byers, John W.   +3 more
core  

Modeling the Internet

open access: yes, 2005
We model the Internet as a network of interconnected Autonomous Systems which self-organize under an absolute lack of centralized control. Our aim is to capture how the Internet evolves by reproducing the assembly that has led to its actual structure and,
Boguna, Marian   +2 more
core   +2 more sources

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

LoRa Communications as an Enabler for Internet of Drones towards Large-Scale Livestock Monitoring in Rural Farms [PDF]

open access: gold, 2021
Mehran Behjati   +5 more
openalex   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

Improved Pedestrian Dead Reckoning Based on a Robust Adaptive Kalman Filter for Indoor Inertial Location System

open access: yesSensors, 2019
Pedestrian dead reckoning (PDR) systems based on a microelectromechanical-inertial measurement unit (MEMS-IMU) providing advantages of full autonomy and strong anti-jamming performance are becoming a feasible choice for pedestrian indoor positioning.
Qigao Fan   +8 more
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

A texture guided transmission line image enhancement method

open access: yesScientific Reports
With the increasing demand of transmission line inspection, image detection technology plays a crucial role in foreign object detection on transmission lines.
Yu Zhang   +4 more
doaj   +1 more source

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